Comparative study of feline spinal cord tumors for distinction between peripheral nerve sheath tumor and meningioma

被引：0

作者：

Saito, Ryo ^{[1
]}

Chambers, James K. ^{[1
]}

Uchida, Kazuyuki ^{[1
]}

机构：

[1] Univ Tokyo, Grad Sch Agr & Life Sci, Lab Vet Pathol, 1-1-1 Yayoi,Bunkyo Ku, Tokyo 1138657, Japan

来源：

JOURNAL OF VETERINARY MEDICAL SCIENCE | 2025年 / 87卷 / 07期

关键词：

cat; differential diagnosis; immunohistochemistry; meningioma; peripheral nerve sheath tumor; INTRACRANIAL MENINGIOMAS; CANINE; NEOPLASMS; FEATURES;

D O I：

10.1292/jvms.25-0082

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

Peripheral nerve sheath tumors (PNSTs) and meningiomas in feline spinal canal are sometimes difficult to differentiate solely on the basis of histopathology. In this study, immunohistochemical markers for differentiating PNSTs from meningiomas were investigated. In the control group, non-spinal PNSTs were immunoreactive for S100 and GFAP but not for E-cadherin, whereas intracranial meningiomas were immunoreactive for E-cadherin but not for S100 and GFAP. In the spinal tumor group, 2/7 cases were immunoreactive for S100 and GFAP but not for E-cadherin and were considered PNSTs. In addition, 5/7 cases were immunoreactive for E-cadherin and not for S100 and GFAP and were considered meningiomas. Immunohistochemistry for S100, GFAP and E-cadherin may aid in the differential diagnosis of feline spinal PNSTs and meningiomas.

引用

页码：747 / 751

页数：5

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