Chemical composition, antioxidant, and antibacterial activities of Cladanthus mixtus essential oil

被引:0
作者
Kamari, Fatima E. L. [1 ]
Bouchyoua, Abdelghani [2 ]
El Amrani, Jihane [3 ]
Harmouzi, Anjoud [3 ]
Tahiri, Nor El Houda [4 ]
Sbai, Amal [5 ]
El-Shazly, Mohamed [6 ]
Aly, Shaza H. [7 ]
El Moussaoui, Abdelfettah [8 ]
Lyoussi, Badiaa [1 ]
Ousaaid, Driss [9 ]
机构
[1] Sidi Mohamed Ben Abdellah Univ, Fac Sci Dhar El Mahraz, Dept Biol, Lab Nat Subst Pharmacol Environm Modeling Hlth & Q, Fes 30000, Morocco
[2] Sidi Mohamed Ben Abdallah Univ, Polydisciplinary Fac Taza, Lab Nat Resources & Environm, Taza 35000, Morocco
[3] Ibn Tofail Univ, Fac Sci, Agrophysiol Biotechnol Environm & Qual Lab, BP 242, Kenitra, Morocco
[4] Ibn Tofail Univ, Fac Sci, Dept Biol, Nat Resources & Sustainable Dev Lab, BP 242, Kenitra, Morocco
[5] Ibn Tofail Univ, Fac Sci, Nat Resources & Sustainable Dev, BP 242, Kenitra, Morocco
[6] Ain Shams Univ, Fac Pharm, Dept Pharmacognosy, Org African Unity St, Cairo 11566, Egypt
[7] Badr Univ Cairo BUC, Fac Pharm, Dept Pharmacognosy, Cairo 11829, Egypt
[8] Abdelmalek Essaadi Univ, Fac Sci, Plant Biotechnol Team, Tetouan 93002, Morocco
[9] Sidi Mohamed Ben Abdellah Univ, Fac Med Pharm & Dent Med, Lab Drug Sci, Fes, Morocco
关键词
Cladanthus mixtus; Essential oil; Antioxidant activity; Antibacterial activity; MIXTUS ESSENTIAL OIL; IN-VITRO;
D O I
10.1016/j.bse.2025.105076
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Medicinal plants constitute an inexhaustible reservoir of phytochemicals with multiple biological properties that have been evoked traditionally and proven scientifically. The current study was conducted to assess the volatile profile of Cladanthus mixtus essential oil collected from the Guercif region for its aromatic constituents using GC/ MS, as well as its antioxidant and antibacterial activities. Chromatographic analysis revealed that the most abundant volatile compound was alpha-pinene (77.30 %). In the DPPH, FRAP, and ABTS assays, the IC50 values at 0.41 +/- 0.02 mg/ml, 0.98 +/- 0.06 mg/ml, and 2.01 +/- 0.04 mg/ml, respectively. The essential oil was also effective against S. aureus and C. koseri with MIC value of 0.187 mg/ml for both bacterial strains. The present investigation indicates that C. mixtus can be a potential natural source of bioactive compounds for product-grade antioxidants for pharmaceutical applications.
引用
收藏
页数:6
相关论文
共 39 条
[1]   In vitro and in vivo studies of Syzygium cumini-loaded electrospun PLGA/PMMA/collagen nanofibers for accelerating topical wound healing [J].
Abdelazim, Esraa B. ;
Abed, Tasneem ;
Goher, Shaimaa S. ;
Alya, Shaza H. ;
El-Nashar, Heba A. S. ;
EL-Moslamy, Shahira H. ;
El-Fakharany, Esmail M. ;
Abdul-Baki, Enas A. ;
Shakweer, Marwa Mosaad ;
Eissa, Noura G. ;
Elsabahy, Mahmoud ;
Kamoun, Elbadawy A. .
RSC ADVANCES, 2024, 14 (01) :101-117
[2]  
Adams R. P., 2007, Identification of essential oil components by gas chromatography/mass spectrometry
[3]  
Aly S., 2020, Phytochemical Investigation Using GC/MS Analysis and Evaluation of Antimicrobial and Cytotoxic Activities of the Lipoidal Matter of Leaves of Sophora secundiflora and Sophora tomentosa, V4, P207
[4]   Chemical composition and biological activity of lemongrass volatile oil and n-Hexane extract: GC/MS analysis, in vitro and molecular modelling studies [J].
Aly, Shaza H. ;
Uba, Abdullahi Ibrahim ;
Nilofar, Nilofar ;
Majrashi, Taghreed A. ;
El Hassab, Mahmoud A. ;
Eldehna, Wagdy M. ;
Zengin, Gokhan ;
Eldahshan, Omayma A. .
PLOS ONE, 2025, 20 (02)
[5]   Comparative metabolic study of the chloroform fraction of three Cystoseira species based on UPLC/ESI/MS analysis and biological activities [J].
Aly, Shaza H. ;
Elissawy, Ahmed M. ;
El Hassab, Mahmoud A. ;
Majrashi, Taghreed A. ;
Hassan, Fatma E. ;
Elkaeed, Eslam B. ;
Eldehna, Wagdy M. ;
Singab, Abdel Nasser B. .
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2024, 39 (01)
[6]   Variability of the Chemical Composition of the Essential Oils of Flowers and the Alkaloid Contents of Leaves ofSophora secundifloraandSophora tomentosa [J].
Aly, Shaza H. ;
Elissawy, Ahmed M. ;
Eldahshan, Omayma A. ;
Elshanawany, Mohamed A. ;
Singab, Abdel Nasser B. .
JOURNAL OF ESSENTIAL OIL BEARING PLANTS, 2020, 23 (03) :442-452
[7]   GC/MS Profiling of the Essential Oil and Lipophilic Extract of Moricandia sinaica Boiss. and Evaluation of Their Cytotoxic and Antioxidant Activities [J].
Aly, Shaza H. H. ;
Kandil, Nariman H. H. ;
Hemdan, Roqaya M. M. ;
Kotb, Sara S. S. ;
Zaki, Sara S. S. ;
Abdelaziz, Omnia M. M. ;
AbdelRazek, Mohamed M. M. ;
Almahli, Hadia ;
El Hassab, Mahmoud A. A. ;
Al-Rashood, Sara T. T. ;
Binjubair, Faizah A. A. ;
Eldehna, Wagdy M. M. .
MOLECULES, 2023, 28 (05)
[8]   Chemical profile, antioxidant and antimicrobial effects of essential oil from the Moroccan endemic plant cladanthus scariosus (L.) [J].
Bellioua, S. ;
Amari, S. ;
Warda, K. ;
Aghraz, A. ;
Dilagui, I ;
Ouhaddou, S. ;
Sissi, S. ;
Bekkouche, K. ;
Larhsini, M. ;
Markouk, M. .
JOURNAL OF ESSENTIAL OIL RESEARCH, 2022, 34 (05) :394-404
[9]  
Borges MFDA., 2022, Med Sci Forum, V12, P11, DOI [10.3390/eca2022-12709, DOI 10.3390/ECA2022-12709]
[10]   Chemical Profile, Antioxidant and Antifungal Activity of Essential Oil from Cladanthus eriolepis [J].
Chibane, El Mustapha ;
Ouknin, Mohamed ;
Renucci, Franck ;
Costa, Jean ;
Majidi, Lhou .
JOURNAL OF ESSENTIAL OIL BEARING PLANTS, 2020, 23 (06) :1296-1305