Frontal theta oscillations and cognitive flexibility: Age-related modulations in EEG activity

被引：0

作者：

Darna, Margarita ^{[1
]}

Stolz, Christopher ^{[1
,2
]}

Jauch, Hannah-Sophia ^{[1
]}

Strumpf, Hendrik ^{[1
,3
]}

Hopf, Jens-Max ^{[1
,2
,3
]}

Schott, Bjorn H. ^{[4
,5
,6
,9
]}

Seidenbecher, Constanze I. ^{[1
,4
,7
,8
]}

Richter, Anni ^{[1
,7
,8
]}

机构：

[1] LIN, Magdeburg, Germany

[2] Otto von Guericke Univ, Inst Psychol, Magdeburg, Germany

[3] Otto von Guericke Univ, Clin Neurol, Magdeburg, Germany

[4] CBBS, Magdeburg, Germany

[5] German Ctr Neurodegenerat Dis DZNE, Tubingen, Germany

[6] Univ Med Ctr Gottingen, Dept Psychiat & Psychotherapy, Gottingen, Germany

[7] German Ctr Mental Hlth DZPG, Partner Site Halle Jena Magdeburg, Magdeburg, Germany

[8] Ctr Intervent & Res Adapt & Maladapt Brain Circuit, Halle Jena Magdeburg, Germany

[9] Otto von Guericke Univ, Dept Psychiat & Psychotherapy, Magdeburg, Germany

来源：

AGING BRAIN | 2025年 / 8卷

关键词：

Theta power; Cognitive flexibility; Set-shifting; Electroencephalography (EEG); Healthy aging; ANTERIOR CINGULATE; EXECUTIVE FUNCTION; OLDER-ADULTS; PERFORMANCE; MEMORY; POWER; ACCURACY; DYNAMICS; REGIONS; ATROPHY;

D O I：

10.1016/j.nbas.2025.100142

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

Cognitive flexibility, the ability to adapt one's behaviour in changing environments, declines during aging. Electroencephalography (EEG) studies have implicated midfrontal theta oscillations in attentional set-shifting, a measure of cognitive flexibility. Little is known about the electrocortical underpinnings of set-shifting in aging. Here, we investigated aging effects on set-shifting performance by analysing theta power in 20 young (mean age: 22.5 +/- 2.9 years) and 19 older (mean age: 69.4 +/- 6.1 years) adults. Increasing shift difficulty (i.e., intra- vs. extra-dimensional shifts) elicited worse performance in both age groups, with older adults showing overall longer reaction times (RTs) and increased RT variability. Young adults exhibited amplified midfrontal theta power increases with higher shift difficulty whereas older adults showed overall lower theta power and no task-related midfrontal theta power modulation, indicating potentially distinct underlying neural mechanisms.

引用

页数：14

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