Pattern of disease and predictors of mortality among critically ill geriatric patients admitted to intensive care unit at a teaching hospital in Ethiopia: a retrospective cohort study

被引:0
作者
Zegeye, Sitotaw Tesfa [1 ]
Nega, Meseret Hulualem [1 ]
Debas, Simachew Amogne [1 ]
Derseh, Mulat Mossie [1 ]
Endeshaw, Amanuel Sisay [1 ]
机构
[1] Bahir Dar Univ, Coll Med & Hlth Sci, Dept Anesthesia, Bahir Dar, Ethiopia
关键词
Mortality; Ethiopia; GERIATRIC MEDICINE; Adult intensive & critical care; ELDERLY-PATIENTS; COMORBIDITY; OUTCOMES; FRAILTY; IMPACT; AGE;
D O I
10.1136/bmjopen-2025-099038
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective This study aimed to assess the pattern of disease and predictors of mortality among critically ill geriatric patients admitted to the intensive care unit at a teaching hospital. Design A single-centre retrospective cohort study. Setting Medical-surgical intensive care unit of Tibebe Ghion Specialized Hospital, Bahir Dar, Ethiopia. Participants We enrolled 296 critically ill patients (age 60+) admitted to the intensive care unit who stayed for more than 2 hours. Those patients with missing or incomplete records were excluded. Primary outcome measure The primary outcome of this study was the time to death within 30 days following intensive care unit admission. Results In this cohort, the overall mortality rate of geriatric patients in the intensive care unit was found to be 42.9%. The incidence rate of mortality was 6.3 deaths per 100 person-days observation. Acute kidney injury (adjusted HR=2.36, 95% CI: 1.16, 3.68), coexisting diseases (adjusted HR=1.66, 95% CI: 1.13, 2.42), the presence of shock (adjusted HR=2.27, 95% CI: 1.66, 4.53) and mechanical ventilation (adjusted HR=1.82, 95% CI: 1.14, 2.89) were predictors of mortality in the intensive care unit. Conclusions The mortality rate in the intensive care unit among geriatric patients was high. Predictors of mortality in this population of critically ill geriatric patients included acute kidney injury, the presence of shock, coexisting diseases and mechanical ventilation in the intensive care unit.
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共 47 条
[1]   Factors predicting mortality in elderly patients admitted to a Moroccan medical intensive care unit [J].
Belayachi, Jihane ;
El Khayari, Mina ;
Dendane, Tarek ;
Madani, Naoufel ;
Abidi, Khalid ;
Abouqal, Redouane ;
Zeggwagh, Amine Ali .
SOUTHERN AFRICAN JOURNAL OF CRITICAL CARE, 2012, 28 (01) :22-27
[2]  
Bettelli G, 2011, MINERVA ANESTESIOL, V77, P637
[3]   Predictive factors of in-hospital mortality in older patients admitted to a medical intensive care unit [J].
Bo, M ;
Massaia, M ;
Raspo, S ;
Bosco, F ;
Cena, P ;
Molaschi, M ;
Fabris, F .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2003, 51 (04) :529-533
[4]   Elderly Patients and Management in Intensive Care Units (ICU): Clinical Challenges [J].
Brunker, Lucille B. ;
Boncyk, Christina S. ;
Rengel, Kimberly F. ;
Hughes, Christopher G. .
CLINICAL INTERVENTIONS IN AGING, 2023, 18 :93-112
[5]  
Campbell EJ, 2011, PRINCIPLES AND PRACTICE OF GERIATRIC SURGERY, SECOND EDITION, P595, DOI 10.1007/978-1-4419-6999-6_47
[6]   Advanced age affects the outcome-predictive power of RIFLE classification in geriatric patients with acute kidney injury [J].
Chao, Chia-Ter ;
Wu, Vin-Cent ;
Lai, Chun-Fu ;
Shiao, Chih-Chung ;
Huang, Tao-Min ;
Wu, Pei-Chen ;
Tsai, I-Jung ;
Hou, Chun-Cheng ;
Wang, Wei-Jie ;
Tsai, Hung-Bin ;
Lin, Yu-Feng ;
Chiang, Wen-Chih ;
Lin, Shuei-Liong ;
Tsai, Pi-Ru ;
Ko, Wen-Je ;
Wu, Ming-Shiou ;
Wu, Kuan-Dun .
KIDNEY INTERNATIONAL, 2012, 82 (08) :920-927
[7]   Multimorbidity Patterns in Hospitalized Older Patients: Associations among Chronic Diseases and Geriatric Syndromes [J].
Clerencia-Sierra, Mercedes ;
Calderon-Larranaga, Amaia ;
Martinez-Velilla, Nicolas ;
Vergara-Mitxeltorena, Itziar ;
Aldaz-Herce, Pablo ;
Poblador-Plou, Beatriz ;
Machon-Sobrado, Monica ;
Eguees-Olazabal, Nerea ;
Abellan-van Kan, Gabor ;
Prados-Torres, Alexandra .
PLOS ONE, 2015, 10 (07)
[8]   Evaluation of ventilator-associated pneumonia care practice in the intensive care units of a comprehensive specialized hospital in Northwest Ethiopia: a 1.5-year prospective observational study [J].
Debas, Simachew Amogne ;
Zeleke, Mulualem Endeshaw ;
Mersha, Abraham Tarekegn ;
Melesse, Debas Yaregal ;
Admassie, Belete Muluadam ;
Workie, Misganaw Mengie ;
Chekol, Wubie Birlie ;
Admass, Biruk Adie .
BMC ANESTHESIOLOGY, 2024, 24 (01)
[9]   Comprehensive geriatric assessment for older adults admitted to hospital [J].
Ellis, Graham ;
Gardner, Mike ;
Tsiachristas, Apostolos ;
Langhorne, Peter ;
Burke, Orlaith ;
Harwood, Rowan H. ;
Conroy, Simon P. ;
Kircher, Tilo ;
Somme, Dominique ;
Saltvedt, Ingvild ;
Wald, Heidi ;
O'Neill, Desmond ;
Robinson, David ;
Shepperd, Sasha .
COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2017, (09)
[10]   The impact of cormorbid conditions on critical illness [J].
Esper, Annette M. ;
Martin, Greg S. .
CRITICAL CARE MEDICINE, 2011, 39 (12) :2728-2735