共 90 条
Cancer Symptom Clusters in Children and Adolescents with Cancer Undergoing Chemotherapy: A Systematic Review
被引:0
作者:
Lopes-Junior, Luis Carlos
[1
,2
]
Grassi, Jonathan
[2
]
Freitas, Marcela Bortoleto
[1
]
Trigo, Fernanda Ercilia Souza
[1
]
Jardim, Fabrine Aguilar
[3
]
Nunes, Karolini Zuqui
[1
]
de Vasconcelos, Karla Anacleto
[2
]
Lima, Regina Aparecida Garcia de
[3
]
机构:
[1] Fed Univ Espirito Santo UFES, Hlth Sci Ctr, Grad Program Nutr & Hlth, BR-29040091 Vitoria, ES, Brazil
[2] Fed Univ Espirito Santo UFES, Hlth Sci Ctr, Grad Program Publ Hlth, BR-29040091 Vitoria, ES, Brazil
[3] Univ Sao Paulo, Ribeirao Preto Coll Nursing, BR-14040902 Ribeirao Preto, SP, Brazil
关键词:
child;
adolescent;
neoplasms;
antineoplastic agents;
concurrent symptoms;
oncology nursing;
QUALITY-OF-LIFE;
CHILDHOOD-CANCER;
PEDIATRIC CANCER;
SICKNESS BEHAVIOR;
YOUNG-ADULTS;
FATIGUE;
SLEEP;
SEVERITY;
EXPERIENCES;
SURVIVORS;
D O I:
10.3390/nursrep15050163
中图分类号:
R47 [护理学];
学科分类号:
1011 ;
摘要:
Objective: To synthesize and analyze the prevalence, composition, longitudinal stability, and predictors of cancer symptom clusters in children and adolescents undergoing chemotherapy. Method: A systematic literature review was conducted in accordance with the PRISMA 2020 guidelines. Evidence was sourced from MEDLINE/PubMed, Cochrane Library, Embase, PsycINFO, and Web of Science, as well as clinical trial registries (Clinical Trials WHO-ICTRP) and gray literature. The search was performed in February 2025, with no restrictions on publication date or language. Two independent reviewers screened and selected the studies. The methodological quality of the included studies was assessed using design-specific tools, and the findings were synthesized narratively. Results: A total of 6221 records were identified, with 12 studies meeting the inclusion criteria. These studies were published between 2010 and 2024 in the United States, Brazil, China, and Turkey. Cancer symptom clusters in children and adolescents followed well-defined patterns, with the gastrointestinal, emotional, fatigue-related, somatic, and self-image clusters being the most prevalent. Conclusions: Early identification of these cancer symptom clusters is essential for guiding interprofessional teams in delivering personalized, evidence-based care to children and adolescents with cancer and their families.
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