Short Anagen Hair Syndrome and Its Association With WNT10A Gene Variants: A Report of Three Pediatric Cases

被引：0

作者：

Roman Mendoza, Nelly Marlene ^{[1
]}

Louka, Magdalini ^{[1
]}

Garcia-Gonzalez, Sergio ^{[1
]}

Ortiz-Cabrera, Nelmar-Valentina ^{[2
]}

Garoz, Barbara Fernandez ^{[2
]}

Noguera-Morel, Lucero ^{[1
]}

Hernandez-Martin, Angela ^{[1
]}

机构：

[1] Hosp Infantil Univ Nino Jesus, Dept Dermatol, Madrid, Spain

[2] Hosp Infantil Univ Nino Jesus, Dept Genet, Madrid, Spain

来源：

PEDIATRIC DERMATOLOGY | 2025年

关键词：

hair disorders; short anagen hair syndrome; trichogram; WNT10A;

D O I：

10.1111/pde.15976

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Short anagen hair syndrome (SAHS) is a rare hair disorder characterized by a shortened anagen phase, limiting hair growth to a few centimeters. SAHS is a benign condition often improving after puberty, with diagnosis supported by clinical, trichological, and genetic findings. We report three pediatric cases of persistently short hair, all with negative hair pull tests and trichogram findings revealing club-shaped roots, tapering, and hair shaft diameter variability. Genetic testing identified the c.682 T>A;p.(Phe228Ile) variant in heterozygosity in the WNT10A gene in two patients, a variant reported as a risk factor for the condition.

引用

页数：3

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