Fluorometric/19F MRI probes for imaging of amyloid-β fibrils

被引：0
作者：
Zeng, Fei [1 ]
He, Shuxin [1 ]
Liu, Bing [1 ]
Zhang, Zirui [1 ]
Guo, Tao [1 ]
Zhang, Jie [1 ]
Wang, Sujuan [2 ]
Zhang, Yuangong [1 ]
机构：
[1] Hebei Univ, Sch Basic Med Sci, Key Lab Pathogenesis Mech & Control Inflammatory A, 180 Wusi East Rd, Baoding 071002, Peoples R China
[2] Hebei Univ, Coll Chem & Mat Sci, 180 Wusi East Rd, Baoding 071002, Peoples R China
来源：
CHEMISTRY LETTERS | 2025年 / 54卷 / 04期
基金：
中国国家自然科学基金;
关键词：
amyloid-beta fibrils; fluorescent probe; F-19; MRI; A-BETA;
D O I：
10.1093/chemle/upaf071
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Aggregation-induced emission and MRI probes are powerful tools that can provide comprehensive and precise diagnostic information for diseases. To address this, we designed and synthesized 2 bimodal imaging probes combining aggregation-induced emission fluorescence imaging and 19F MRI for detecting beta-amyloid fibrils.
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页数：5
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