Gefitinib for EGFR mutated lung adenocarcinoma during pregnancy: A case report with 5-Year Follow-Up

被引:0
作者
Messekher, Merouane [1 ]
Fuchs, Florent [2 ,3 ,4 ]
Badr, Maliha [5 ]
Pujol, Jean-Louis [1 ]
机构
[1] Montpellier Univ, Univ Hosp Montpellier, Thorac Oncol Unit, Montpellier, France
[2] Montpellier Univ, Univ Hosp Montpellier, Dept Obstet & Gynecol, Montpellier, France
[3] INSERM, U1018, CESP Ctr Res Epidemiol & Populat Hlth, Reprod & Child Dev, Villejuif, France
[4] Univ Montpellier, INSERM, DESBREST Inst Epidemiol & Publ Hlth IDESP, Montpellier, France
[5] Montpellier Univ, Univ Hosp Montpellier, Neonatal Pediat Dept, Montpellier, France
关键词
Lung adenocarcinoma; Pregnancy; Gefitinib; Targeted therapy; EGFR-TKI;
D O I
10.1016/j.lungcan.2025.108456
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
We report the case of a 37-year-old pregnant woman at 19 weeks of gestation who was diagnosed with a stage M1b EFGRmut lung adenocarcinoma, in 2019. After a right upper and middle bilobectomy (T3N1 and R0 pathological status) and a complete cerebellar metastasis resection, she was treated with gefitinib, which offered her a prolonged recurrence-free survival without any negative consequence for the fetal development or the future development of her now 5-year-old child.
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页数:3
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