Respiratory syncytial virus infection, non-respiratory syncytial virus respiratory infections, and later wheezing

被引:0
作者
Takahashi, Ippei [1 ]
Shinoda, Genki [1 ,2 ]
Ueno, Fumihiko [2 ]
Matsuzaki, Fumiko [2 ]
Noda, Aoi [1 ,2 ,3 ]
Murakami, Keiko [2 ]
Ishikuro, Mami [1 ,2 ]
Obara, Taku [1 ,2 ,3 ]
Nakayama, Yoshikazu [4 ]
Momose, Atsushi [4 ]
Tsuchiya, Naho [2 ]
Nagaie, Satoshi [5 ]
Ogishima, Soichi [5 ]
Tamiya, Gen [6 ,7 ]
Fuse, Nobuo [6 ]
Hozawa, Atsushi [2 ,8 ,9 ]
Sugawara, Junichi [10 ]
Kure, Shigeo [11 ]
Kuriyama, Shinichi [1 ,2 ,12 ]
机构
[1] Tohoku Univ, Grad Sch Med, Div Mol Epidemiol, Sendai, Japan
[2] Tohoku Univ, Dept Prevent Med & Epidemiol, Tohoku Med Megabank Org, 2-1 Seiryo Machi,Aoba Ku, Sendai 9808573, Japan
[3] Tohoku Univ Hosp, Dept Pharmaceut Sci, Sendai, Japan
[4] Janssen Pharmaceut KK, R&D Clin Sci Div, Tokyo, Japan
[5] Tohoku Univ, Dept Hlth Record Informat, Tohoku Med Megabank Org, Sendai, Japan
[6] Tohoku Univ, Dept Integrat Genom, Tohoku Med Megabank Org, Sendai, Japan
[7] RIKEN, Ctr Adv Intelligence Project, Tokyo, Japan
[8] Tohoku Univ, Grad Sch Med, Div Epidemiol, Sendai, Japan
[9] Tohoku Univ, Grad Sch Med, Div Personalized Prevent & Epidemiol, Sendai, Japan
[10] Suzuki Mem Hosp, Iwanuma, Japan
[11] Miyagi Childrens Hosp, Sendai, Japan
[12] Tohoku Univ, Int Res Inst Disaster Sci, Sendai, Japan
关键词
birth cohort; epidemiology; respiratory syncytial virus; RSV; wheezing; TRACT INFECTIONS; RSV BRONCHIOLITIS; ASTHMA; HOSPITALIZATION; RISK; ASSOCIATION; BIRTH;
D O I
10.1111/ped.70050
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
BackgroundStudies investigating whether respiratory syncytial virus (RSV) infection, non-RSV respiratory infections, respiratory-related disorders, and non-respiratory-related disorders are associated with subsequent wheezing are limited in Japan. We aimed to elucidate the relationship between hospitalization for RSV infection, non-RSV respiratory infections, respiratory-related disorders, as well as non-respiratory-related disorders and subsequence wheezing in Japanese children.MethodsThis study included 7340 children and was conducted under the TMM BirThree Cohort Study (Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study). Data was collected from birth records and questionnaires. We categorized hospitalization history into five categories: "no hospitalization," hospitalizations for "RSV infection," "non-RSV respiratory infections," "respiratory-related disorders," and "non-respiratory-related disorders." The association of the five categories with later wheezing at 3 years of age was evaluated using multivariable logistic regression analysis.ResultsAfter adjusting for covariates, an association was shown between hospitalization under 2 years of age and later wheezing (odds ratio [OR] = 2.78; 95% confidence interval [CI] = 1.97-3.88 for "RSV infection"; OR = 2.61; 95% CI = 1.44-4.57 for "non-RSV respiratory infections"; and OR = 3.33; 95% CI = 2.43-4.54 for "respiratory-related disorders").ConclusionHospitalization of children under 2 years of age for RSV infection as well as non-RSV respiratory infections and respiratory-related disorders were associated with subsequent wheezing.
引用
收藏
页数:6
相关论文
共 26 条
[1]   INTERNATIONAL STUDY OF ASTHMA AND ALLERGIES IN CHILDHOOD (ISAAC) - RATIONALE AND METHODS [J].
ASHER, MI ;
KEIL, U ;
ANDERSON, HR ;
BEASLEY, R ;
CRANE, J ;
MARTINEZ, F ;
MITCHELL, EA ;
PEARCE, N ;
SIBBALD, B ;
STEWART, AW ;
STRACHAN, D ;
WEILAND, SK ;
WILLIAMS, HC .
EUROPEAN RESPIRATORY JOURNAL, 1995, 8 (03) :483-491
[2]   Adults face increased asthma risk after infant RSV bronchiolitis and reduced respiratory health-related quality of life after RSV pneumonia [J].
Backman, Katri ;
Piippo-Savolainen, Eija ;
Ollikainen, Hertta ;
Koskela, Heikki ;
Korppi, Matti .
ACTA PAEDIATRICA, 2014, 103 (08) :850-855
[3]  
Brunwasser SM, 2020, LANCET RESP MED, V8, P795, DOI 10.1016/S2213-2600(20)30109-0
[4]   The Long-Term Healthcare Utilization and Economic Burden of RSV Infection in Children ≤5 Years in Japan: Propensity Score Matched Cohort Study [J].
Chirikov, Viktor ;
Botteman, Marc ;
Simoes, Eric A. F. .
CLINICOECONOMICS AND OUTCOMES RESEARCH, 2022, 14 :699-714
[5]   Wheezing following lower respiratory tract infections with respiratory syncytial virus and influenza A in infancy [J].
Eriksson, M ;
Bennet, R ;
Nilsson, A .
PEDIATRIC ALLERGY AND IMMUNOLOGY, 2000, 11 (03) :193-197
[6]   RISK OF PRIMARY INFECTION AND REINFECTION WITH RESPIRATORY SYNCYTIAL VIRUS [J].
GLEZEN, WP ;
TABER, LH ;
FRANK, AL ;
KASEL, JA .
AMERICAN JOURNAL OF DISEASES OF CHILDREN, 1986, 140 (06) :543-546
[7]   Association of Rhinovirus C Bronchiolitis and Immunoglobulin E Sensitization During Infancy With Development of Recurrent Wheeze [J].
Hasegawa, Kohei ;
Mansbach, Jonathan M. ;
Bochkov, Yury A. ;
Gern, James E. ;
Piedra, Pedro A. ;
Bauer, Cindy S. ;
Teach, Stephen J. ;
Wu, Susan ;
Sullivan, Ashley F. ;
Camargo, Carlos A., Jr. .
JAMA PEDIATRICS, 2019, 173 (06) :544-552
[8]   Hospitalization for RSV bronchiolitis before 12 months of age and subsequent asthma, atopy and wheeze: A longitudinal birth cohort study [J].
Henderson, J ;
Hilliard, TN ;
Sherriff, A ;
Stalker, D ;
Shammari, NA ;
Thomas, HM .
PEDIATRIC ALLERGY AND IMMUNOLOGY, 2005, 16 (05) :386-392
[9]   Strategic Methods for Recruiting Grandparents: The Tohoku Medical Megabank Birth and Three-Generation Cohort Study [J].
Ishikuro, Mami ;
Obara, Taku ;
Osanai, Tamae ;
Yamanaka, Chizuru ;
Sato, Yuki ;
Mizuno, Satoshi ;
Miyashita, Masako ;
Kikuya, Masahiro ;
Sakurai, Kasumi ;
Hozawa, Atsushi ;
Tomita, Hiroaki ;
Taki, Yasuyuki ;
Nagami, Fuji ;
Metoki, Hirohito ;
Kuriyama, Shinichi .
TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE, 2018, 246 (02) :97-105
[10]   Epidemiology of respiratory syncytial virus in Japan: A nationwide claims database analysis [J].
Kobayashi, Yasuhiro ;
Togo, Kanae ;
Agosti, Yasmeen ;
McLaughlin, John M. .
PEDIATRICS INTERNATIONAL, 2022, 64 (01)