Incidence and risk factors for surgical wound complications in women with body mass index >30 kg/m2 following cesarean delivery: a secondary analysis

被引:1
作者
Gillespie, Brigid M. [1 ,2 ]
Ellwood, David [3 ,4 ]
Thalib, Lukman [5 ]
Kumar, Sailesh [6 ]
Mahomed, Kassam [7 ]
Kang, Evelyn [8 ]
Chaboyer, Wendy [9 ]
机构
[1] Griffith Univ, Ctr Res Excellence Wiser Wound Care, Natl Hlth & Med Res Council, Gold Coast Campus, Gold Coast, Qld, Australia
[2] Griffith Univ, Menzies Hlth Inst Queensland, Gold Coast Campus, Gold Coast, Qld, Australia
[3] Griffith Univ, Sch Med & Dent, Gold Coast, Qld, Australia
[4] Gold Coast Univ Hosp, Gold Coast, Qld, Australia
[5] Istanbul Aydin Univ, Fac Med, Dept Biostat, Istanbul, Turkiye
[6] Univ Queensland, Mater Res Inst, Brisbane, Australia
[7] Univ Queensland, Fac Med, Brisbane, Australia
[8] Mater MothersHospital, South Brisbane, Qld, Australia
[9] Univ Queensland, Ipswich Hosp, Fac Med, Dept Obstet & Gynaecol, Ipswich, Qld, Australia
来源
AJOG GLOBAL REPORTS | 2022年 / 2卷 / 03期
基金
英国医学研究理事会;
关键词
cesarean delivery; cumulative incidence; obesity; predictor; wound breakdown; wound disruption; wound infection; wound separation; DOUBLE-LAYER CLOSURE; SITE INFECTION; SECTION; DEHISCENCE; THERAPY; CORONIS;
D O I
10.1016/j.xagr.2022.100069
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
BACKGROUND: Surgical wound complications are common and occur in between 3% and 12% of obese women after cesarean delivery. An understanding of the risk factors for wound complications may inform potential areas for clinical care improvement. OBJECTIVE: This study aimed to identify the incidence and predictors of surgical wound complications in obese women after cesarean delivery. STUDY DESIGN: This was a secondary analysis of the ADding negative pRESSure to improve healING, or DRESSING, randomized controlled trial conducted at 4 maternity hospitals in Australia. A total of 2035 women with a prepregnancy body mass index >= 30 kg/m2 undergoing cesarean delivery were included. Data were collected between October 2015 and December 2019 using self-reporting of signs and symptoms, the research nurses' direct observation of the surgical site, and medical records. Independent blinded outcome assessors ascertained wound outcomes on the basis of self-reported data and medical records. Multivariable logistic regression models were used to identify independent risk factors for wound complications and surgical wound dehiscence. The 30-day cumulative incidence of wound complications and surgical wound dehiscence was calculated. RESULTS: Of the 2035 women, 317 (15.6%) developed a wound complication, whereas 211 (10.4%) developed surgical wound dehiscence. The predictors of a wound complication included 1 previous cesarean delivery (odds ratio, 1.41; 95% confidence interval, 1.05-1.90; P=.02) and ruptured membranes >12 hours (odds ratio, 1.69; 95% confidence interval, 1.08-2.66; P=.02). The odds of developing any wound complication decreased by 45% with vaginal cleansing (odds ratio, 0.55; 95% confidence interval, 0.42-0.72; P<.001) and by 59% for low transverse incision (odds ratio, 0.41; 95% confidence interval, 0.18-0.94; P=.04). The predictors of surgical wound dehiscence included 1 previous cesarean delivery (odds ratio, 1.62; 95% confidence interval, 1.14-2.31; P=.008) and ruptured membranes >12 hours (odds ratio, 1.85; 95% confidence interval, 1.10-3.12; P=.02). The odds of developing surgical wound dehiscence decreased by 50% for vaginal cleansing (odds ratio, 0.50; 95% confidence interval, 0.36-0.69; P<.001) and by 42% for using a double-layer uterine closure (odds ratio, 0.58; 95% confidence interval, 0.35-0.97; P=.04). CONCLUSION: Wound complications and surgical wound dehiscence in this population are high. The predictors observed herein would assist in identifying high-risk women. Such information may guide patient-centered decision-making in the planning of surgical births and individualized postoperative care.
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页数:8
相关论文
共 39 条
[1]   Caesarean section surgical techniques: 3 year follow-up of the CORONIS fractional, factorial, unmasked, randomised controlled trial [J].
Abalos, E. ;
Addo, V. ;
Brocklehurst, P. ;
El Sheikh, M. ;
Mathews, J. E. ;
Masood, S. Naz ;
Oyarzun, E. ;
Oyieke, J. ;
Sharma, J. B. ;
Ashworth, F. ;
Brocklehurst, P. ;
Derrick, D. Chippington ;
Cousens, S. ;
Farrell, B. ;
Juszczak, E. ;
Neilson, J. ;
Purwar, M. ;
Roberts, M. ;
Waddington, C. ;
Abalos, E. ;
Addo, V. ;
Brocklehurst, P. ;
El Sheikh, M. ;
Farrell, B. ;
Gray, S. ;
Hardy, P. ;
Juszczak, E. ;
Mathews, J. E. ;
Masood, S. Naz ;
Oyarzun, E. ;
Oyieke, J. ;
Sharma, J. B. ;
Spark, P. ;
Brocklehurst, P. ;
Farrell, B. ;
Gray, S. ;
Hardy, P. ;
Howard, S. ;
Jamieson, N. ;
Juszczak, E. ;
Spark, P. ;
Roberts, T. .
LANCET, 2016, 388 (10039) :62-72
[2]  
Alfouzan W, 2019, Epidemiol Infect, V147, pe287, DOI 10.1017/S0950268819001675
[3]   Prevena™, negative pressure wound therapy applied to closed Pfannenstiel incisions at time of caesarean section in patients deemed at high risk for wound infection [J].
Anglim, B. ;
O'Connor, H. ;
Daly, S. .
JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 2015, 35 (03) :255-258
[4]  
[Anonymous], 2019, HLTH GLANCE 2019 OEC, DOI DOI 10.1787/4DD50C09-EN
[5]   Caesarean section surgical techniques (CORONIS): a fractional, factorial, unmasked, randomised controlled trial [J].
Arias, C. A. ;
Bosquiazzo, L. M. ;
Bruna, J. A. ;
Fabrica, M. C. ;
Mascotti, C. ;
Bertin, M. S. ;
Castaldi, J. L. ;
Mendoza, S. J. ;
Partida, L. Y. ;
Zyla, A. ;
Castilla, L. ;
Di Gerolano, E. ;
Espinoza, M. ;
Koch, G. ;
Tulian, M. ;
Melis, M. ;
Miriam, M. ;
Palermo, M. ;
Pappalardo, J. ;
Quinones, M. ;
Cabrera, F. ;
Campos, S. ;
Curioni, M. A. ;
Fernandez, J. ;
Grasselli, C. ;
Abarzua, F. ;
Araya, G. ;
Caro, M. ;
Gonzalez, C. ;
Vera, C. ;
Araneda, M. ;
De la Cuadra, S. ;
Kusanovic, J. P. ;
Ortiz, J. A. ;
Silva, K. ;
Bofa, W. K. ;
Djokoto, R. M. ;
Konney, T. O. ;
Larbi, Y. O. ;
Quashie, E. ;
Kriplani, A. ;
Kumar, S. ;
Mittal, S. ;
Gupta, U. ;
Puri, M. ;
Raghunandan, C. ;
Trivedi, S. S. ;
Batra, S. ;
Kumar, A. ;
Manaktala, U. .
LANCET, 2013, 382 (9888) :234-248
[6]   Caesarean section surgical techniques: a randomised factorial trial (CAESAR) [J].
Brocklehurst, Peter ;
Quigley, Maria ;
Ayers, Sarah ;
Juszczak, Ed .
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 2010, 117 (11) :1366-1376
[7]   Risks factors FOR wound complications after cesarean section [J].
Carbonnel, Marie ;
Brot, Domitille ;
Benedetti, Charlotte ;
Kennel, Titouan ;
Murtada, Rouba ;
Revaux, Aurelie ;
Ayoubi, Jean-Marc .
JOURNAL OF GYNECOLOGY OBSTETRICS AND HUMAN REPRODUCTION, 2021, 50 (07)
[8]  
Centers for Disease Control and Prevention, 2022, Defining adult overweight and obesity
[9]   Incidence and predictors of surgical site infection in women who are obese and give birth by elective caesarean section: A secondary analysis [J].
Chaboyer, Wendy ;
Ellwood, David ;
Thalib, Lukman ;
Kumar, Sailesh ;
Mahomed, Kassam ;
Kang, Evelyn ;
Gillespie, Brigid M. .
AUSTRALIAN & NEW ZEALAND JOURNAL OF OBSTETRICS & GYNAECOLOGY, 2022, 62 (02) :234-240
[10]   Negative Pressure Wound Therapy on Surgical Site Infections in Women Undergoing Elective Caesarean Sections: A Pilot RCT [J].
Chaboyer, Wendy ;
Anderson, Vinah ;
Webster, Joan ;
Sneddon, Anne ;
Thalib, Lukman ;
Gillespie, Brigid M. .
HEALTHCARE, 2014, 2 (04) :417-428