Multisystem immune-related adverse reactions with immune checkpoint inhibitors

被引：0

作者：

Jayson, Amy ^{[1
]}

Tsambarlis, Maria ^{[1
]}

Thakkar, Hardik ^{[1
]}

Ludlow, Steven P. ^{[1
]}

Syed, Misbahuddin ^{[1
]}

机构：

[1] H Lee Moffitt Canc Ctr & Res Inst, Tampa, FL 33612 USA

来源：

JAAPA-JOURNAL OF THE AMERICAN ACADEMY OF PHYSICIAN ASSISTANTS | 2025年 / 38卷 / 06期

关键词：

immune checkpoint inhibitors; immune-related adverse reactions; nivolumab; ipilimumab; oncology; dermatitis; EVENTS;

D O I：

10.1097/01.JAA.0000000000000211

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Immune checkpoint inhibitors have transformed oncologic practice, producing durable responses in many patients with advanced malignancies. However, these treatments can cause immune-related adverse reactions. This article describes a patient with metastatic non-small cell lung cancer who developed toxicities involving multiple organ systems shortly after receiving combined ipilimumab and nivolumab. Although toxicity is more common in just one organ system, multisystem adverse reactions are possible, and clinicians who recognize and manage these reactions promptly can improve patient outcomes.

引用

页码：29 / 31

页数：3