Neuromodulation on the ground and in the clouds: a mini review of transcranial direct current stimulation for altering performance in interactive driving and flight simulators

Transcranial direct current stimulation (tDCS) has emerged as a promising tool for cognitive enhancement, especially within simulated virtual environments that provide realistic yet controlled methods for studying human behavior. This mini review synthesizes current research on the application of tDCS to improve performance in interactive driving and flight simulators. The existing literature indicates that tDCS can enhance acute performance for specific tasks, such as maintaining a safe distance from another car or executing a successful plane landing. However, the effects of tDCS may be context-dependent, indicating a need for a broader range of simulated scenarios. Various factors, including participant expertise, task difficulty, and the targeted brain region, can also influence tDCS outcomes. To further strengthen the rigor of this research area, it is essential to address and minimize different forms of research bias to achieve true generalizability. This comprehensive analysis aims to bridge the gap between theoretical understanding and practical application of neurotechnology to study the relationship between the brain and behavior, ultimately providing insights into the effectiveness of tDCS in transportation settings.