Effects of mindfulness-based interventions on cognitive impairment in patients with cancer: A systematic review and meta-analysis

被引：2
作者：
Jiang, Shuqin [1 ]
Sun, Yaoyao [4 ]
Yu, Lixiang [5 ,6 ]
Hu, Xinjie [1 ]
Li, Jie [1 ,2 ,3 ]
机构：
[1] Shandong Univ, Cheeloo Coll Med, Sch Publ Hlth, Dept Social Med & Hlth Management, Jinan, Peoples R China
[2] Shandong Univ, NHC Key Lab Hlth Econ & Policy Res, Jinan, Peoples R China
[3] Shandong Univ, Ctr Hlth Management & Policy Res, Shandong Prov Key New Think Tank, Jinan, Peoples R China
[4] Peking Univ, Peking Univ Inst Mental Hlth, Peking Univ Hosp 6, NHC Key Lab Mental Hlth,Natl Clin Res Ctr Mental D, Beijing, Peoples R China
[5] Shandong Univ, Dept Breast Surg, Hosp 2, Jinan, Shandong, Peoples R China
[6] Shandong Univ, Inst Translat Med Breast Dis Prevent & Treatment, Jinan, Shandong, Peoples R China
来源：
INTERNATIONAL JOURNAL OF CLINICAL AND HEALTH PSYCHOLOGY | 2025年 / 25卷 / 02期
基金：
中国国家自然科学基金;
关键词：
Cancer; Cognitive function; Cognitive impairment; Mindfulness interventions; Meta-analysis; Quality of life; Systematic review; QUALITY-OF-LIFE; STRESS REDUCTION MBSR; BREAST-CANCER; WOMEN; COMPLEMENTARY; SURVIVORS; BENEFITS; THERAPY; FATIGUE; PROGRAM;
D O I：
10.1016/j.ijchp.2025.100576
中图分类号：
B849 [应用心理学];
学科分类号：
040203 ;
摘要：
Background: Cognitive impairment has been widely reported among cancer survivors, significantly impacting their quality of life. Mindfulness interventions are increasingly used to alleviate cognitive impairment in patients with cancer. This study aimed to assess the effects of mindfulness interventions on cognitive impairment in patients with cancer post-intervention and at follow-up.<br /> Methods: Up until February 2024, five English databases (PubMed, Web of Science, Embase, Cochrane, and PsycINFO) and three Chinese databases (CNKI, Wan Fang, and CBM) were searched to identify relevant studies. To determine the effect size, we used random effects model to compute the standardized mean difference and 95 % confidence intervals. Results: We included 23 randomized controlled trials and seven non-randomized controlled trials. Mindfulness interventions significantly improved patients' subjective cognitive function post-intervention (SMDbetween-group=0.81, 95 %CI: 0.58 to 1.03; SMDwithin-group=1.12, 95 %CI: 0.71 to 1.52) and at follow-up (SMDbetween-group=0.39, 95 %CI: 0.09 to 0.68; SMDwithin-group=0.59, 95 %CI: 0.35 to 0.82). Subgroup analysis indicated significantly larger effect of the interventions in developing countries than those in developed countries (pbetween-group=0.014; pwithin-group=0.008), and of the interventions without additional home practice than those with home practice in within-group comparisons (pbetween-group=0.217; pwithin-group=0.018). There were no significant differences in the effects between interventions lasting >= eight weeks and < eight weeks (pbetween-group=0.093; pbetween-group=0.303). However, no significant effects were observed on objective cognitive function. Conclusions: Mindfulness-based interventions can effectively improve the subjective cognitive function in cancer patients both post-intervention and at follow-up. Future intervention research should take into account regions, home practice, and intervention duration.
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页数：12
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