A renal transplant recipient with a pulmonic valve mass

被引：0

作者：

Darwish, Ilyse ^{[1
,8
]}

de Varennes, Benoit ^{[2
]}

Fiset, Pierre Olivier ^{[3
]}

Camilleri-Broet, Sophie ^{[3
]}

Lash, Vynka ^{[4
]}

Cantarovich, Marcelo ^{[5
]}

Lee, Todd C. ^{[6
,7
]}

Costiniuk, Cecilia T. ^{[6
,7
]}

机构：

[1] St Marys Hosp, Dept Med, Div Infect Dis, Montreal, PQ, Canada

[2] McGill Univ Hlth Ctr, Dept Surg, Montreal, PQ, Canada

[3] McGill Univ Hlth Ctr, Dept Pathol, Montreal, PQ, Canada

[4] McGill Univ Hlth Ctr, Dept Anaesthesia, Montreal, PQ, Canada

[5] McGill Univ Hlth Ctr, Dept Med, Div Nephrol, Montreal, PQ, Canada

[6] McGill Univ Hlth Ctr, Infect Dis & Immun Global Hlth Program, Res Inst, Montreal, PQ, Canada

[7] McGill Univ Hlth Ctr, Dept Med, Div Infect Dis, Quebec City, PQ, Canada

[8] St Marys Hosp, 3830 Lacombe Ave, Montreal, PQ H3T 1M5, Canada

来源：

CARDIOVASCULAR PATHOLOGY | 2025年 / 78卷

关键词：

Infective endocarditis; Aspergillosis; Invasive Aspergillosis; Pulmonic valve endocarditis; Blood culture-negative endocarditis; ENDOCARDITIS; DIAGNOSIS; ASPERGILLOSIS; MANAGEMENT;

D O I：

10.1016/j.carpath.2025.107745

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 43-year-old female with a renal transplant presented with fatigue, dyspnea, anemia, and thrombocytopenia. Chest CT revealed pulmonary nodules, and transthoracic echocardiography identified a large, multi-lobulated, multi-cystic mass attached to the pulmonic valve. Pathology demonstrated fungal hyphae, and bronchoalveolar lavage (BAL) fluid grew Aspergillus fumigatus, with a serum Aspergillus galactomannan (GM) antigen index of 1.95. The pulmonic valve was excised and a bioprosthetic valve was inserted. The patient was treated with voriconazole. Pulmonic valve Aspergillus endocarditis (AE) is a rare condition associated with high mortality. Given the rising number of transplant recipients, heightened clinical vigilance is warranted in this population.

引用

页数：3

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