Prevalence of cardiac dysfunction in men with erectile dysfunction: the EDcard study

被引:0
作者
Durukan, Emil [1 ,2 ,3 ]
Jensen, Christian Fuglesang S. [1 ]
Dons, Maria [2 ,4 ]
Sengelov, Morten [2 ,4 ]
Landler, Nino Emanuel [2 ,4 ]
Skaarup, Kristoffer Grundtvig [2 ,4 ]
Hojbjerg Lassen, Mats C. [2 ,4 ]
Johansen, Niklas Dyrby [2 ,4 ]
Ostergren, Peter Busch [1 ,3 ]
Sonksen, Jens [1 ,3 ]
Fode, Mikkel [1 ,3 ]
Biering-Sorensen, Tor [2 ,4 ,5 ,6 ]
机构
[1] Copenhagen Univ Hosp Herlev & Gentofte, Dept Urol, Borgmester Ib Juuls Vej 23A, DK-2730 Herlev, Denmark
[2] Copenhagen Univ Hosp Herlev & Gentofte, Dept Cardiol, Cardiovasc Noninvas Imaging Res Lab, Herlev, Denmark
[3] Univ Copenhagen, Inst Clin Med, Fac Hlth & Med Sci, Copenhagen, Denmark
[4] Univ Copenhagen, Fac Hlth & Med Sci, Ctr Translat Cardiol & Pragmat Randomized Trials, Dept Biomed Sci, Copenhagen, Denmark
[5] Copenhagen Univ Hosp, Steno Diabet Ctr, Rigshospitalet, Copenhagen, Denmark
[6] Copenhagen Univ Hosp, Rigshospitalet, Dept Cardiol, Copenhagen, Denmark
关键词
erectile dysfunction; cardiovascular disease; cardiac disease; cardiac dysfunction; echocardiography; two-dimensional speckle tracking echocardiography; global longitudinal strain; VENTRICULAR DIASTOLIC FUNCTION; EUROPEAN ASSOCIATION; EJECTION FRACTION; AMERICAN SOCIETY; STRAIN; ECHOCARDIOGRAPHY; RECOMMENDATIONS; RISK; METAANALYSIS; UPDATE;
D O I
10.1111/bju.16824
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
ObjectivesTo assess the prevalence of myocardial impairment in men with erectile dysfunction (ED) as compared with the general population using conventional and two-dimensional speckle-tracking echocardiography. Subjects and MethodsIn this cross-sectional study, men with ED underwent clinical, electrocardiographic, and transthoracic echocardiographic evaluation including left ventricular ejection fraction (LVEF) and global longitudinal strain (GLS) according to a predefined protocol. All participants were matched 1:1 with controls from the general population on sex, age, and body mass index (BMI). ResultsIn total, 796 people were included, 398 men with ED and 398 controls. The ED group had a median (interquartile range [IQR]) age of 61 (53-70) years and a median (IQR) BMI of 26.3 (24-29) kg/m(2). Left ventricular (LV) systolic dysfunction was found in 232 (58.3%) men with ED compared to 102 (25.6%) controls (P < 0.001). Nineteen (4.8%) men with ED were referred for further cardiovascular evaluation. ConclusionMore than half of men with ED exhibited signs of cardiac dysfunction, particularly LV systolic dysfunction. Further research should explore the long-term prognostic implications of these findings.
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页数:8
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