Risk factors contributing to the persistent infection of high-risk Human papillomavirus (HPV)

被引：0

作者：

Feng, Ting ^{[1
]}

Yang, Yuhong ^{[1
]}

机构：

[1] Hangzhou Womens Hosp, Dept Obstet & Gynecol, Hangzhou 310008, Zhejiang, Peoples R China

来源：

EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY | 2025年 / 46卷 / 05期

关键词：

Human papillomavirus; Cervical cancer; Persistent infection; CARCINOMA IN-SITU; CERVICAL-CANCER; VIRAL LOAD; ASSOCIATION; GRADE; LESIONS; WOMEN; DNA; HUMAN-PAPILLOMAVIRUS-16; PREVALENCE;

D O I：

10.22514/ejgo.2025.060

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Human papillomavirus (HPV) infection in the reproductive tract is one of the most prevalent sexually transmitted infections worldwide. Persistent infection with high-risk HPV (HR-HPV) types is a major contributor of cervical cancer and its precancerous lesions. The severity and progression of these lesions are closely linked to multiple HPV infections and viral load. Emerging research indicates that the persistence of HRHPV infection is influenced not only by viral genetic mutations and trait variations but also by host immune response and genetic factors. Investigations into these risk factors are gaining momentum and hold promise for breakthroughs in the diagnosis and identification of prognostic markers for cervical cancer. This review provides a comprehensive overview of recent advancements in this field.

引用

页码：1 / 7

页数：7

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