Synthesis, characterization and antibacterial study of novel 2-((E)-2-(thiophen-2-yl)vinyl)-4H-chromen-4-ones

被引：0
作者：
Endait, R. S. [1 ]
机构：
[1] Radhabai Kale Mahila Mahavidyalaya, PG Dept Chem, Ahmednagar 414001, India
来源：
INDIAN JOURNAL OF CHEMISTRY | 2025年 / 64卷 / 06期
关键词：
Thiophene; 1,3-Diketones; Styrylchromones; Antibacterial activity; PHARMACOLOGICAL EVALUATION; BIOLOGICAL-ACTIVITIES; DERIVATIVES; 2-STYRYLCHROMONES; AGENTS; THIOPHENE; DESIGN;
D O I：
10.56042/ijc.v64i6.16492
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A new series of 2-((E)-2-(thiophen-2-yl)vinyl)-4H-chromen-4-ones have been synthesized and characterized by mass, IR, H-1 and C-13 NMR spectroscopy. The characterization data supports the formation of synthesized compounds. All the synthesized compounds have been investigated for antibacterial activity against Pseudomonas flurescence (NCIM 2059), Escherichia coli (NCIM 2576) as Gram negative and Staphylococcus aureus (NCIM 2602), Bacillus subtilis (NCIM 2162) as Gram positive bacteria at different concentrations and they show moderate to good antibacterial activity.
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收藏
页码：619 / 626
页数：8
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