Efficacy of low-intensity extracorporeal shock wave therapy for erectile dysfunction: updated meta-analysis of randomized trials

被引:0
作者
Fatima, Kaneez [1 ]
Abbas, Zahra [1 ]
Un-Noor, Anjum [1 ]
Aaqil, Syeda Ilsa [2 ]
Amir, Rabia [2 ]
Nawaz, Farzeen [2 ]
Zafar, Summiya [2 ]
Ali, Hafsa [2 ]
Rashid, Ahmed Mustafa [2 ]
机构
[1] Dow Univ Hlth Sci, Dept Med, Karachi, Pakistan
[2] Jinnah Sindh Med Univ, Dept Med, Karachi, Pakistan
关键词
Randomized controlled trials; meta-analysis; Li-ESWT; low-intensity extracorporeal shock wave therapy; erectile dysfunction; DOUBLE-BLIND; NITRIC-OXIDE; ASSOCIATION;
D O I
10.1080/20565623.2025.2511438
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
BackgroundLow-intensity extracorporeal shockwave therapy (Li-ESWT) is proposed for the treatment of erectile dysfunction (ED).Materials and methodsRandomized controlled trials (RCTs) that compared Li-ESWT with sham therapy in patients with vasculogenic ED were included. The International Index of Erectile Function - Erectile Function (IIEF-EF) domain score, increase in the Erection Hardness Score (EHS), and improvement in Sexual Encounter Profile (SEP) 2 and SEP-3 were assessed.ResultsThis meta-analysis of 12 RCTs, including 882 men with vasculogenic ED, demonstrated a statistically significant improvement in IIEF-EF score (an improvement from baseline as well as MCID) and EHS (patients with EHS >= 3) following LI-ESWT compared to sham therapy.ConclusionThe results support the role of Li-ESWT as a potential treatment for ED.
引用
收藏
页数:14
相关论文
共 44 条
[1]  
[Anonymous], 1955, Ir J Med Sci, V30, P47, DOI [10.1007/BF02952758, DOI 10.1007/BF02952758]
[2]   Selective Interception of Gelsolin Amyloidogenic Stretch Results in Conformationally Distinct Aggregates with Reduced Toxicity [J].
Arya, Prabha ;
Srivastava, Ankit ;
Vasaikar, Suhas V. ;
Mukherjee, Goutam ;
Mishra, Prashant ;
Kundu, Bishwajit .
ACS CHEMICAL NEUROSCIENCE, 2014, 5 (10) :982-992
[3]  
Aytac IA, 1999, BJU INT, V84, P50
[4]   Association of type and duration of diabetes with erectile dysfunction in a large cohort of men [J].
Bacon, CG ;
Hu, FB ;
Giovannucci, E ;
Glasser, DB ;
Mittleman, MA ;
Rimm, EB .
DIABETES CARE, 2002, 25 (08) :1458-1463
[5]   Erectile Dysfunction: AUA Guideline [J].
Burnett, Arthur L. ;
Nehra, Ajay ;
Breau, Rodney H. ;
Culkin, Daniel J. ;
Faraday, Martha M. ;
Hakim, Lawrence S. ;
Heidelbaugh, Joel ;
Khera, Mohit ;
McVary, Kevin T. ;
Miner, Martin M. ;
Nelson, Christian J. ;
Sadeghi-Nejad, Hossein ;
Seftel, Allen D. ;
Shindel, Alan W. .
JOURNAL OF UROLOGY, 2018, 200 (03) :633-641
[6]  
Cartledge J, 2001, Expert Opin Pharmacother, V2, P95, DOI 10.1517/14656566.2.1.95
[7]   1ST CLINICAL-EXPERIENCE WITH EXTRACORPOREALLY INDUCED DESTRUCTION OF KIDNEY-STONES BY SHOCK-WAVES [J].
CHAUSSY, C ;
SCHMIEDT, E ;
JOCHAM, D ;
BRENDEL, W ;
FORSSMANN, B ;
WALTHER, V .
JOURNAL OF UROLOGY, 1982, 127 (03) :417-420
[8]   A Prospective, Randomized, Double-Blinded, Clinical Trial Using a Second-Generation Duolith SD1 Low-Intensity Shockwave Machine in Males with Vascular Erectile Dysfunction [J].
Chung, Eric ;
Bailey, William ;
Wang, Juan .
WORLD JOURNAL OF MENS HEALTH, 2023, 41 (01) :94-100
[9]   Nitric oxide mediates anti-inflammatory action of extracorporeal shock waves [J].
Ciampa, AR ;
de Prati, AC ;
Amelio, E ;
Cavalieri, E ;
Persichini, T ;
Colasanti, M ;
Musci, G ;
Marlinghaus, E ;
Suzuki, H ;
Mariotto, S .
FEBS LETTERS, 2005, 579 (30) :6839-6845
[10]   Effects of Low-Intensity Extracorporeal Shockwave Therapy on Erectile Dysfunction: A Systematic Review and Meta-Analysis [J].
Clavijo, Raul I. ;
Kohn, Taylor P. ;
Kohn, Jaden R. ;
Ramasamy, Ranjith .
JOURNAL OF SEXUAL MEDICINE, 2017, 14 (01) :27-35