Gut microbiota plays a key role in the development of colorectal cancer

被引：0

作者：

Liu, Ying-Ling ^{[1
]}

Liu, Jie ^{[1
]}

机构：

[1] Univ Sci & Technol China, Univ Sci & Technol China USTC, Affiliated Hosp 1, Dept Gastroenterol,Div Life Sci & Med, 17 Lujiang Rd, Hefei 230001, Anhui, Peoples R China

来源：

WORLD JOURNAL OF GASTROENTEROLOGY | 2025年 / 31卷 / 14期

关键词：

Colorectal cancer; Gut microbiota; Microbial dysbiosis; Intratumoral microbiota; Gut metabolites; METABOLITES;

D O I：

10.3748/wjg.v31.i14.105420

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

This letter addresses the recently published manuscript by Darnindro et al, which investigates the diversity and composition of colonic mucosal microbiota in Indonesian patients with and without colorectal cancer (CRC). Although the analysis revealed no statistically significant differences in alpha diversity between the CRC and non-CRC groups, the authors identified notable distinctions in the composition and diversity of colonic mucosal microbiota among patients with CRC compared to those without. At the genus level, a statistically significant difference in microbiota composition was documented between the two cohorts. Specifically, the genera Bacteroides, Campylobacter, Peptostreptococcus, and Parvimonas were found to be elevated in individuals with CRC, while Faecalibacterium, Haemophilus, and Phocaeicola were more prevalent in the non- CRC group.

引用

页数：5

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