Characteristics of neonatal-onset and presumed neonatal arterial ischemic stroke

被引：0

作者：

Ueda, Kazuto ^{[1
]}

Kataoka, Erina ^{[1
]}

Natsume, Jun ^{[1
,2
,3
]}

Hori, Ikumi ^{[1
,4
,5
]}

Tsuji, Takeshi ^{[1
,6
]}

Miyake, Misa ^{[1
,7
]}

Suzuki, Michio ^{[1
,8
]}

Kobayashi, Satoru ^{[1
,9
]}

Kurahashi, Hirokazu ^{[1
,10
]}

Sato, Yoshiaki

Okumura, Akihisa ^{[10
,11
]}

Yoshikawa, Tetsushi ^{[7
]}

Saitoh, Shinji ^{[4
]}

Takahashi, Yoshiyuki ^{[2
]}

机构：

[1] Nagoya Univ Hosp, Ctr Maternal Neonatal Care, Div Neonatol, Nagoya, Japan

[2] Pediat Stroke Study Grp Aichi Prefecture, Nagoya, Aichi, Japan

[3] Nagoya Univ, Grad Sch Med, Dept Pediat, 65 Tsurumai Cho,Showa Ku, Nagoya, Aichi 4668550, Japan

[4] Nagoya Univ, Grad Sch Med, Dept Dev Disabil Med, Nagoya, Japan

[5] Nagoya City Univ, Grad Sch Med Sci, Dept Pediat & Neonatol, Nagoya, Japan

[6] Aichi Prefectural Welf Federat Agr Cooperat, Kainan Hosp, Dept Hematol, Yatomi, Japan

[7] Aichi Prefectural Mikawa Aoitori Med & Rehabil Ct, Dept Pediat, Okazaki, Japan

[8] Fujita Hlth Univ, Sch Med, Dept Pediat, Toyoake, Aichi, Japan

[9] Anjo Kosei Hosp, Dept Hematol & Oncol, Anjo, Japan

[10] Nagoya City Univ West Med Ctr, Dept Rehabil, Nagoya, Japan

[11] Aichi Med Univ, Dept Pediat, Nagakute, Japan

来源：

BRAIN & DEVELOPMENT | 2025年 / 47卷 / 03期

关键词：

Neonatal arterial ischemic stroke; Presumed neonatal arterial ischemic stroke; Magnetic resonance imaging; Precentral gyrus; Basal ganglia; Posterior limb of the internal capsule; Hemiplegia; Intellectual disability; Neurodevelopmental disorder; HUMAN COAGULATION SYSTEM; RISK-FACTORS; PERINATAL STROKE; FULL-TERM;

D O I：

10.1016/j.braindev.2025.104343

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Objective: To clarify the difference in clinical-radiological features between neonatal-onset arterial ischemic stroke (AIS) and presumed neonatal AIS with a normal neonatal neurological history. Methods: Twenty-one neonatal AIS patients and seven with presumed neonatal AIS were identified in Aichi Prefecture, Japan, between 2010 and 2014. MRI and clinical characteristics were determined. Results: Nine patients (43 %) with neonatal AIS and only one patient (13 %) with presumed neonatal AIS underwent emergency cesarean sections (ECS). Pyramidal tract involvement was more common in patients with presumed neonatal AIS (71 %) than in those with neonatal AIS (24 %). The most common sequela, hemiplegia, was present in 33 % of patients with neonatal AIS and 71 % with presumed neonatal AIS. Conclusions: The small number of ECS in presumed neonatal AIS suggests different causal factors from those of neonatal AIS. Given the different distributions of lesions and sequelae, there can be undiagnosed patients with presumed neonatal AIS and no sequelae.

引用

页数：6

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