Chemical Sensors and Biosensors for Point-of-Care Testing of Pets: Opportunities for Individualized Diagnostics of Companion Animals

被引：2
作者：
Fonseca, Wilson Tiago [1 ]
Parra Vello, Tatiana [2 ]
Lelis, Gabrielle Coelho [1 ,3 ]
Deleigo, Ana Vitoria Ferreira [1 ,4 ]
Takahira, Regina Kiomi [5 ]
Martinez, Diego Stefani Teodoro [1 ]
de Oliveira, Rafael Furlan [1 ,3 ,4 ,6 ]
机构：
[1] Brazilian Ctr Res Energy & Mat CNPEM, Brazilian Nanotechnol Natl Lab LNNano, BR-13083100 Campinas, Brazil
[2] Mackenzie Presbyterian Inst IPM, Mackenzie Inst Res Graphene & Nanotechnol MackGrap, BR-01302907 Sao Paulo, Brazil
[3] Univ Campinas UNICAMP, Inst Chem IQ, BR-13083862 Campinas, Brazil
[4] Sao Paulo State Univ Julio de Mesquita Filho UNESP, Postgrad Program Mat Sci & Technol POSMAT, BR-17033360 Bauru, Brazil
[5] Sao Paulo State Univ Julio de Mesquita Filho UNESP, Sch Vet Med & Anim Sci, Dept Vet Clin, BR-18618687 Botucatu, Brazil
[6] Univ Campinas UNICAMP, Inst Phys Gleb Wataghin IFGW, BR-13083859 Campinas, Brazil
来源：
ACS SENSORS | 2025年 / 10卷 / 05期
基金：
瑞典研究理事会; 巴西圣保罗研究基金会;
关键词：
point of care testing; lateral flow test; diagnostics; sensors andbiosensors; companion animals; animal healthcare; veterinary diagnostics; onehealth; C-REACTIVE PROTEIN; ELECTROCHEMICAL SENSORS; KIDNEY-DISEASE; VIRUS-ANTIGEN; HUMAN HEALTH; DOGS; CATS; BIOMARKERS; SALIVA; ANTIBODIES;
D O I：
10.1021/acssensors.4c03664
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Point-of-care testing (POCT) is recognized as one of the most disruptive medical technologies for rapid and decentralized diagnostics. Successful commercial examples include portable glucose meters, pregnancy tests, and COVID-19 self-tests. However, compared to advancements in human healthcare, POCT technologies for companion animals (pets) remain significantly underdeveloped. This Review explores the latest advancements in pet POCT and examines the challenges and opportunities in the field for individualized diagnostics of cats and dogs. The most frequent diseases and their respective biomarkers in blood, urine, and saliva are discussed. We examine key strategies for developing the next-generation POCT devices by harnessing the potential of selective (bio)receptors and high-performing transducers such as lateral flow tests and electrochemical (bio)sensors. We also present the most recent research initiatives and the successful commercial pet POCT technologies. We discuss future trends in the field, such the role of biomarker discovery and development of wearable, implantable, and breath sensors. We believe that advancing pet POCT technologies benefits not only animals but also humans and the environment, supporting the One Health approach.
引用
收藏
页码：3222 / 3238
页数：17
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