A postmortem study of patients vaccinated for SARS-CoV-2 in Colombia

被引:3
作者
Chaves, Juan Jose [1 ]
Bonilla, Juan Carlos [1 ]
Chaves-Cabezas, Viviana [1 ]
Castro, Andres [1 ]
Polo, Jose Fernando [1 ]
Mendoza, Oscar [1 ]
Correa-Rodriguez, Jennifer [1 ]
Piedrahita, Ana Carolina [1 ]
Romero-Fandino, Ivan Alberto [1 ]
Caro, Maria Victoria [1 ]
Gonzalez, Andrea Carolina [1 ]
Sanchez, Lisseth Katherine [1 ]
Murcia, Felix [1 ]
Marquez, Gloria [1 ]
Benavides, Alejandra [1 ]
Quiroga, Maria del Pilar [1 ]
Lopez, Jorge [1 ]
Parra-Medina, Rafael [1 ,2 ]
机构
[1] Fdn Univ Ciencias Salud, Hosp San Jose, Dept Pathol, Bogota, Colombia
[2] Fdn Univ Ciencias Salud, Res Inst, Bogota, Colombia
来源
REVISTA ESPANOLA DE PATOLOGIA | 2023年 / 56卷 / 01期
关键词
COVID-19; Clinical autopsy; Immunization; Colombia; SUDDEN CARDIAC DEATH; AUTOPSY;
D O I
10.1016/j.patol.2022.09.003
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
Introduction and objective: A new coronavirus produces a disease designated as coronavirus disease 2019 (COVID-19). Vaccination against COVID-19 has resulted in decreased mortality. Postmortems of vaccinated patients play an important part in the forensic analysis of adverse effects after vaccination, which is essential for determining its efficacy and security. The main objective of this study was to describe the results of autopsies of patients vaccinated for SARSCoV-2 carried out in two major centers in Colombia. Materials and methods: A descriptive cross-sectional study of 121 autopsies was performed following Colombian regulations in two main hospitals in Bogot & aacute;, Colombia, between March 1st and April 31st, 2021. Results: 118 of the 121 patients (97.52%) had been vaccinated with CoronaVac (Sinovac); only 3 had received other vaccines. Sudden cardiac death was the leading cause of death, with pulmonary embolism another critical finding. No relation between the cause of death and vaccination against SARS-CoV-2 was found. Conclusions: A clinical autopsy is a vital for an accurate post-mortem diagnosis. Any relation between the SARS-CoV-2 vaccine and the cause of death should be carefully studied in order to provide the general public with evidence-based information about the safety of the vaccination. (c) 2022 Sociedad Espanola de Anatom<acute accent>& imath;a Patolo<acute accent>gica. Published by Elsevier Espana, S.L.U. All rights reserved.
引用
收藏
页码:4 / 9
页数:6
相关论文
共 28 条
[1]  
[Anonymous], Ministerio de salud y proteccion social, Republica de Colombia
[2]   Sudden Cardiac Death: A Review Focused on Cardiovascular Imaging [J].
Barletta, Valentina ;
Fabiani, Iacopo ;
Lorenzo, Conte ;
Nicastro, Irene ;
Di Bello, Vitantonio .
JOURNAL OF CARDIOVASCULAR ECHOGRAPHY, 2014, 24 (02) :41-51
[3]   Guidelines for autopsy investigation of sudden cardiac death: 2017 update from the Association for European Cardiovascular Pathology [J].
Basso, Cristina ;
Aguilera, Beatriz ;
Banner, Jytte ;
Cohle, Stephan ;
d'Amati, Giulia ;
de Gouveia, Rosa Henriques ;
di Gioia, Cira ;
Fabre, Aurelie ;
Gallagher, Patrick J. ;
Leone, Ornella ;
Lucena, Joaquin ;
Mitrofanova, Lubov ;
Molina, Pilar ;
Parsons, Sarah ;
Rizzo, Stefania ;
Sheppard, Mary N. ;
Suarez Mier, Maria Paz ;
Suvarna, S. Kim ;
Thiene, Gaetano ;
van der Wal, Allard ;
Vink, Aryan ;
Michaud, Katarzyna .
VIRCHOWS ARCHIV, 2017, 471 (06) :691-705
[4]   Analysis of COVID-19 Vaccine Type and Adverse Effects Following Vaccination [J].
Beatty, Alexis L. ;
Peyser, Noah D. ;
Butcher, Xochitl E. ;
Cocohoba, Jennifer M. ;
Lin, Feng ;
Olgin, Jeffrey E. ;
Pletcher, Mark J. ;
Marcus, Gregory M. .
JAMA NETWORK OPEN, 2021, 4 (12)
[5]   Molecular autopsy in sudden cardiac death [J].
Carlos Bonilla, Juan ;
Parra-Medina, Rafael ;
Jose Chaves, Juan ;
Campuzano, Oscar ;
Sarquella-Brugada, Georgia ;
Brugada, Ramon ;
Brugada, Josep .
ARCHIVOS DE CARDIOLOGIA DE MEXICO, 2018, 88 (04) :306-312
[6]   Current burden of sudden cardiac death: Multiple source surveillance versus retrospective death certificate-based review in a large US community [J].
Chugh, SS ;
Jui, J ;
Gunson, K ;
Stecker, EC ;
John, BT ;
Thompson, B ;
Ilias, N ;
Vickers, C ;
Dogra, V ;
Daya, M ;
Kron, J ;
Zheng, ZJ ;
Mensah, G ;
McAnulty, J .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2004, 44 (06) :1268-1275
[7]   SARS-CoV-2 Vaccine-Induced Immune Thrombotic Thrombocytopenia [J].
Cines, Douglas B. ;
Bussel, James B. .
NEW ENGLAND JOURNAL OF MEDICINE, 2021, 384 (23) :2254-2256
[8]  
Costache Mariana, 2014, Maedica (Bucur), V9, P261
[9]   Deaths associated with newly launched SARS-CoV-2 vaccination (Comirnaty®) [J].
Edler, Carolin ;
Klein, Anke ;
Schroder, Ann Sophie ;
Sperhake, Jan-Peter ;
Ondruschka, Benjamin .
LEGAL MEDICINE, 2021, 51
[10]   Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China [J].
Huang, Chaolin ;
Wang, Yeming ;
Li, Xingwang ;
Ren, Lili ;
Zhao, Jianping ;
Hu, Yi ;
Zhang, Li ;
Fan, Guohui ;
Xu, Jiuyang ;
Gu, Xiaoying ;
Cheng, Zhenshun ;
Yu, Ting ;
Xia, Jiaan ;
Wei, Yuan ;
Wu, Wenjuan ;
Xie, Xuelei ;
Yin, Wen ;
Li, Hui ;
Liu, Min ;
Xiao, Yan ;
Gao, Hong ;
Guo, Li ;
Xie, Jungang ;
Wang, Guangfa ;
Jiang, Rongmeng ;
Gao, Zhancheng ;
Jin, Qi ;
Wang, Jianwei ;
Cao, Bin .
LANCET, 2020, 395 (10223) :497-506