Extracorporeal membrane oxygenation for systemic lupus erythematosus: An ELSO registry analysis

被引：0

作者：

Pereira, Maria ^{[1
]}

Guffey, Danielle ^{[2
]}

Doane, Katherine ^{[3
]}

Muscal, Eyal ^{[1
]}

Levin, Carla ^{[4
]}

Rycus, Peter ^{[5
]}

Anders, Marc ^{[5
]}

Ontaneda, Andrea ^{[3
]}

机构：

[1] Baylor Coll Med, Div Pediat Rheumatol, Houston, TX USA

[2] Baylor Coll Med, Inst Clin & Translat Res, Houston, TX USA

[3] Baylor Coll Med, Div Pediat Crit Care, Houston, TX USA

[4] Baylor Coll Med, Dept Pediat, Houston, TX USA

[5] Extracorporeal Life Support Org, Ann Arbor, MI USA

来源：

PERFUSION-UK | 2025年

关键词：

Systemic Lupus Erythematosus; lupus; extracorporeal membrane oxygenation; extracorporeal life support; ELSO registry; IMMUNOCOMPROMISED PATIENTS; LIFE-SUPPORT; MYOCARDITIS; CHILDREN; PATIENT;

D O I：

10.1177/02676591251346069

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The success of extracorporeal membrane oxygenation (ECMO) in treating Systemic Lupus Erythematosus (SLE) and the risk factors associated with mortality remain uncertain.Methods: We describe the survival outcomes at discharge of the largest SLE cohort on ECMO support. We performed a retrospective cohort study of the Extracorporeal Life Support Organization registry database from 2012 to 2022. Pediatric and adult survivor groups were analyzed using descriptive statistics for the primary study outcome of survival to hospital discharge. Risk predictors for survival were determined by logistic regression.Results: We included 48 children and 368 adults with SLE. Overall, 198 patients (54%) survived to hospital discharge, with a survival of 52% and 47% of pediatric and adult patients, respectively.Conclusion: We conclude that ECMO can be considered a life supporting strategy in pediatric and adult SLE patients.

引用

页数：9

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