Type 2 Diabetes Impacts the Efficacy of Syphilis Treatment and is a Risk Factor for Late Syphilis: A Retrospective Cohort Study

被引：0

作者：

Tang, Yijie ^{[1
]}

Wu, Mengxiao ^{[2
]}

Xu, Wenwen ^{[1
]}

Yu, Jiajie ^{[1
]}

Yang, Dandan ^{[1
]}

Zhang, Jiaqin ^{[1
]}

Shen, Lingyun ^{[1
]}

Xie, Qinghui ^{[1
]}

Luo, Qingqiong ^{[1
]}

机构：

[1] Tongji Univ, Shanghai Skin Dis Hosp, Sch Med, Dept Clin Lab Med, Shanghai, Peoples R China

[2] Fudan Univ, Sch Basic Med Sci, Dept Biochem, Shanghai, Peoples R China

来源：

ACTA DERMATO-VENEREOLOGICA | 2025年 / 105卷

关键词：

diabetes; syphilis; cohort study; risk; MANIFESTATIONS; INFECTIONS; PREVENTION;

D O I：

10.2340/actadv.v105.42210

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

This study examined the relationship between type 2 diabetes and late syphilis. A retrospective analysis was conducted, including 96 syphilis patients with type 2 diabetes and 122 matched non-diabetic syphilis controls. The development of late-stage syphilis and responses to initial treatment were monitored over a 2-year period. Stratified logistic regression was used to assess whether diabetes increased the risk of late syphilis. Differences in initial treatment responses between the 2 groups were evaluated using chi 2 tests and Kaplan-Meier curves. The cohort study confirmed that the serological cure rate within 12 months was significantly lower in diabetic syphilis patients. Type 2 diabetes significantly impacts the efficacy of syphilis treatment and is a risk factor for late syphilis.

引用

页数：7

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