The use of immotile testicular sperm for in vitro fertilization/ intracytoplasmic sperm injection what are the outcomes?

被引：0
作者：
Panken, Evan J. [1 ]
Greenberg, Daniel R. [1 ]
Nam, Catherine S. [1 ]
Hwang, Kathleen [2 ]
Brannigan, Robert E. [1 ]
Halpern, Joshua A. [1 ,3 ]
机构：
[1] Northwestern Univ, Dept Urol, Feinberg Sch Med, 676 N St Clair St,Arkes 2300, Chicago, IL 60611 USA
[2] Univ Penn, Perelman Sch Med, Dept Surg, Div Urol, Philadelphia, PA USA
[3] Poster Hlth, Centennial, CO USA
来源：
F&S REPORTS | 2025年 / 6卷 / 02期
关键词：
Azoospermia; immotile sperm; testicular sperm; in vitro fertilization; intracytoplasmic sperm injection; SPERMATOZOA; MOTILITY; TISSUE; ICSI;
D O I：
10.1016/j.xfre.2025.03.005
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Sperm extraction for in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) remains the only option for men with azoospermia to father biologic offspring. Even in cases of successful sperm retrieval, the challenge of selecting optimal sperm for use in IVF/ICSI is an area of research interest. Testicular sperm, unlike epididymal or ejaculated sperm, are often immotile, and there remains debate on the use of immotile testicular sperm in IVF/ICSI and how to best assess sperm viability. Therefore, we aimed to summarize the available literature regarding IVF/ICSI outcomes using immotile testicular sperm. (F S Rep (R) 2025;6:108-15. (c) 2025 by American Society for Reproductive Medicine.)
引用
收藏
页码：108 / 115
页数：8
相关论文
共 19 条
[1]   Cumulative IVF outcomes after retrieval of testicular spermatozoa: should we use immotile spermatozoa for ICSI? [J].
Aizer, Adva ;
Lazarovich, Alon ;
Dratviman-Storobinsky, Olga ;
Noach-Hirsh, Meirav ;
Haas, Jigal ;
Jacob, Avi ;
Raviv, Gil ;
Orvieto, Raoul .
REPRODUCTIVE BIOMEDICINE ONLINE, 2021, 43 (02) :269-277
[2]  
Borges Júnior Edson, 2002, Sao Paulo Med. J., V120, P122, DOI 10.1590/S1516-31802002000400007
[3]   Planned oocyte cryopreservation: the state of the ART [J].
Cascante, Sarah Druckenmiller ;
Berkeley, Alan S. ;
Licciardi, Frederick ;
McCaffrey, Caroline ;
Grifo, James A. .
REPRODUCTIVE BIOMEDICINE ONLINE, 2023, 47 (06)
[4]   Laser-assisted selection of immotile spermatozoa has no effect on obstetric and neonatal outcomes of TESA-ICSI pregnancies [J].
Chen, Huanhua ;
Wang, Caizhu ;
Zhou, Hong ;
Shu, Jinhui ;
Gan, Xianyou ;
Xu, Kongrong ;
Wu, Zhulian ;
Deng, Xihe ;
Huang, Guiting ;
Lin, Ruoyun .
REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY, 2021, 19 (01)
[5]   The epidemiology and etiology of azoospermia [J].
Cocuzza, Marcello ;
Alvarenga, Conrado ;
Pagani, Rodrigo .
CLINICS, 2013, 68 :15-26
[6]   New insights into epididymal biology and function [J].
Cornwall, Gail A. .
HUMAN REPRODUCTION UPDATE, 2009, 15 (02) :213-227
[7]   Factors affecting outcome after ICSI with spermatozoa retrieved from cryopreserved testicular tissue in non-obstructive azoospermia [J].
Dafopoulos, K ;
Griesinger, G ;
Schultze-Mosgau, A ;
Orief, Y ;
Schöpper, B ;
Nikolettos, N ;
Diedrich, K ;
Al-Hasani, S .
REPRODUCTIVE BIOMEDICINE ONLINE, 2005, 10 (04) :455-460
[8]   Pregnancy with frozen-thawed and fresh testicular biopsy after motile and immotile sperm microinjection, using the mechanical touch technique to assess viability [J].
de Oliveira, NM ;
Sánchez, RV ;
Fiesta, SR ;
Salgado, TL ;
Rodríguez, R ;
Bethencourt, JCA ;
Zamora, RB .
HUMAN REPRODUCTION, 2004, 19 (02) :262-265
[9]   The influence of sperm motility and cryopreservation on the treatment outcome after intracytoplasmic sperm injection following testicular sperm extraction [J].
Hessel, Marloes ;
Robben, Johanna C. M. ;
D'Hauwers, Kathleen W. M. ;
Braat, Didi D. M. ;
Ramos, Liliana .
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA, 2015, 94 (12) :1313-1321
[10]   The Role of the Epididymis and the Contribution of Epididymosomes to Mammalian Reproduction [J].
James, Emma R. ;
Carrell, Douglas T. ;
Aston, Kenneth, I ;
Jenkins, Timothy G. ;
Yeste, Marc ;
Salas-Huetos, Albert .
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 21 (15) :1-17
12