Direct Site-Selective Deoxygenation of Benzylalcohol Derivatives

被引：0

作者：

Yagi, Satoshi ^{[1
]}

Morisaki, Kazuhiro ^{[1
]}

Sato, Yoshihiro ^{[1
]}

机构：

[1] Hokkaido Univ, Fac Pharmaceut Sci, Sapporo, 0600812, Japan

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2025年 / 367卷 / 14期

基金：

日本学术振兴会;

关键词：

deoxygenations; photocatalysis; polyols; site-selectivities; transesterifications; O BOND-CLEAVAGE; MODEL COMPOUNDS; LIGNIN; CHEMISTRY; DEPOLYMERIZATION; DEGRADATION; OXIDATION; CHEMICALS; TOLUATES;

D O I：

10.1002/adsc.9590

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A simple yet efficient method is presented for direct and site-selective deoxygenation of benzyl alcohol derivatives, including polyols, without requiring preactivation. This reaction system, consisting of Hantzsch ester, Cs2CO3, and a photocatalyst under photoirradiation, enables direct and site-selective deoxygenation. Mechanistic studies reveal that in situ reversible acylative activation of hydroxy groups plays a pivotal role in achieving unique selectivity. This approach offers a general and practical strategy for the selective transformation of polyols.

引用

页数：10

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