Clinical marine biomedicine: An emerging area in clinical and translational medicine

被引:0
作者
Yan, Xiaojun [1 ]
Duan, Wanxin [2 ]
Wang, Xiangdong [2 ,3 ,4 ]
机构
[1] Zhejiang Ocean Univ, Sch Marine Sci & Technol, Dept Marine Biotechnol, Zhoushan, Peoples R China
[2] Fudan Univ, Dept Resp Crit Care Med, Zhongshan Hosp, Shanghai Med Coll, Shanghai, Peoples R China
[3] Shanghai Inst Clin Bioinformat, Shanghai, Peoples R China
[4] Fudan Univ, Ctr Clin Bioinformat, Shanghai, Peoples R China
关键词
clinical; disease; human; marine biomedicine; oceanology;
D O I
10.1002/ctm2.70303
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Marine biomedicine is an important field in oceanology and bio-ecosystem and has evolved significantly alongside advances in biotechnology and growing understanding of marine life. In this perspective, we propose a refined concept of clinical marine biomedicine, with a clear mission to establish an emerging discipline that bridges marine biomedicine and clinical practice. The exploration of marine-origin sources should be emphasised, with a strong focus on the identification, validation and development of human disease-specific diagnostics and target-oriented pharmaceutics. The perspective headlines some of critical components, including marine-oriented human evolution and development, humanised marine-based models, biomarker innovation and validation, marine microbiomes and metabolites, and target nutrition and therapy. We envision that clinical marine biomedicine will become a crucial pillar clinical molecular medicine, contributing to the improvement of human health and the prognosis of patient.
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页数:5
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