Research progress on the role of ginsenoside Rd in central nervous system diseases

被引:1
作者
Ma, Xiaoyu [1 ]
Wang, Juejin [2 ]
机构
[1] Nanjing Med Univ, Clin Sch 2, Nanjing 211199, Jiangsu, Peoples R China
[2] Nanjing Med Univ, Dept Physiol, 818 Tianyuan East Rd, Nanjing 211199, Jiangsu, Peoples R China
关键词
Ginsenoside Rd; Stroke; Spinal cord injury; Alzheimer's disease; Parkinson's disease; FOCAL CEREBRAL-ISCHEMIA; STROKE; EXPRESSION; PROTECTS; DAMAGE; CELLS;
D O I
10.4314/ahs.v24i4.41
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Ginsenoside Rd (GSRd) is one of the rare saponin monomers extracted from ginseng. Most importantly, GSRd could effectively cross the intact blood-brain barrier (BBB). Studies have shown that it plays an important role in the treatment of neurological diseases such as ischemic stroke (IS), spinal cord injury (SCI), Alzheimer's disease (AD) and Parkinson's disease (PD). The results of these studies are of great significance for the clinical application of GSRd in the treatment in neurological diseases. This article reviewed the protective effects of GSRd in central nervous system diseases and analysed the related mechanism.
引用
收藏
页码:325 / 331
页数:7
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