The association between body temperature and 28-day mortality in sepsis patients: A retrospective observational study

被引：0

作者：

Yang, Wei ^{[1
]}

Zhou, Dan ^{[1
]}

Peng, Hui ^{[1
]}

Jiang, Huilin ^{[2
]}

Chen, Weifeng ^{[1
]}

机构：

[1] Shenzhen Univ, Affiliated Hosp 1, Shenzhen Peoples Hosp 2, Dept Gen Practice, 3002 Sungang Rd, Shenzhen 518035, Guangdong, Peoples R China

[2] Guangzhou Med Univ, Affiliated Hosp 2, Dept Emergency, 250 Changgang East Rd, Guangzhou 510260, Guangdong, Peoples R China

来源：

MEDICINA INTENSIVA | 2025年 / 49卷 / 04期

关键词：

Body temperature; Sepsis; Nonlinear relationship; Generalized additive model; Smooth curve fitting; CRITICALLY-ILL PATIENTS; SEPTIC SHOCK; ACUTE PHYSIOLOGY; FEVER; MANAGEMENT; HEALTH;

D O I：

10.1016/j.medin.2024.08.011

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Objective: This study explored the association between body temperature and 28-day septic ICU hospital mortality. Design: Retrospective cohort analysis. Setting: 208 ICUs in the United States. Patients or participants: Sepsis patients from 2014-2015 eICU Collaborative Research Database. Interventions: Binary logistic regression models, Generalized Additive Model (GAM), Two-Piece Binary Logistic Regression Model. Main variables of interest: Body temperature, 28-day inpatient mortality. Results: Nonlinear relationship observed; hypothermia (<= 36.67 degrees C) associated with increased mortality (adjusted OR = 0.74, 95% CI: 0.70-0.80, p < 0.0001). Conclusions: Hypothermia in sepsis correlates with higher mortality; rewarming's potential benefit warrants further exploration. (c) 2024 Published by Elsevier Espana, S.L.U.

引用

页码：205 / 215

页数：11

共 29 条

[1]

Beverly A, 2016, J Intensive Care Soc, V17, P88, DOI 10.1177/1751143715601124

[2]

Dallimore J, 2018, CRIT CARE RESUSC, V20, P150

[3] Vital-sign circadian rhythms in patients prior to discharge from an ICU: a retrospective observational analysis of routinely recorded physiological data [J].

Davidson, Shaun ;

Villarroel, Mauricio ;

Harford, Mirae ;

Finnegan, Eoin ;

Jorge, Joao ;

Young, Duncan ;

Watkinson, Peter ;

Tarassenko, Lionel .

CRITICAL CARE, 2020, 24 (01)

[4] Fever in non-neurological critically ill patients: A systematic review of observational studies [J].

Egi, Moritoki ;

Morita, Kiyoshi .

JOURNAL OF CRITICAL CARE, 2012, 27 (05) :428-433

[5]

Evans L, 2021, INTENS CARE MED, V47, P1181, DOI [10.1007/s00134-021-06506-y, 10.1097/CCM.0000000000005337]

[6] Missing covariate data in clinical research: when and when not to use the missing-indicator method for analysis [J].

Groenwold, Rolf H. H. ;

White, Ian R. ;

Donders, Rogier T. ;

Carpenter, James R. ;

Altman, Douglas G. ;

Moons, Karel G. M. .

CANADIAN MEDICAL ASSOCIATION JOURNAL, 2012, 184 (11) :1265-1269

[7] Induced hypothermia in patients with septic shock and respiratory failure (CASS): a randomised, controlled, open-label trial [J].

Itenov, Theis Skovsgaard ;

Johansen, Maria Egede ;

Bestle, Morten ;

Thormar, Katrin ;

Hein, Lars ;

Gyldensted, Louise ;

Lindhardt, Anne ;

Christensen, Henrik ;

Estrup, Stine ;

Pedersen, Henrik Planck ;

Harmon, Matthew ;

Soni, Uday Kant ;

Perez-Protto, Silvia ;

Wesche, Nicolai ;

Skram, Ulrik ;

Petersen, John Asger ;

Mohr, Thomas ;

Waldau, Tina ;

Poulsen, Lone Musaeus ;

Strange, Ditte ;

Juffermans, Nicole P. ;

Sessler, Daniel I. ;

Tonnesen, Else ;

Moller, Kirsten ;

Kristensen, Dennis Karsten ;

Cozzi-Lepri, Alessandro ;

Lundgren, Jens D. ;

Jensen, Jens-Ulrik .

LANCET RESPIRATORY MEDICINE, 2018, 6 (03) :183-192

[8] APACHE-II - A SEVERITY OF DISEASE CLASSIFICATION-SYSTEM [J].

KNAUS, WA ;

DRAPER, EA ;

WAGNER, DP ;

ZIMMERMAN, JE .

CRITICAL CARE MEDICINE, 1985, 13 (10) :818-829

[9] The impact of body temperature abnormalities on the disease severity and outcome in patients with severe sepsis: an analysis from a multicenter, prospective survey of severe sepsis [J].

Kushimoto, Shigeki ;

Gando, Satoshi ;

Saitoh, Daizoh ;

Mayumi, Toshihiko ;

Ogura, Hiroshi ;

Fujishima, Seitaro ;

Araki, Tsunetoshi ;

Ikeda, Hiroto ;

Kotani, Joji ;

Miki, Yasuo ;

Shiraishi, Shin-ichiro ;

Suzuki, Koichiro ;

Suzuki, Yasushi ;

Takeyama, Naoshi ;

Takuma, Kiyotsugu ;

Tsuruta, Ryosuke ;

Yamaguchi, Yoshihiro ;

Yamashita, Norio ;

Aikawa, Naoki .

CRITICAL CARE, 2013, 17 (06)

[10] Association of body temperature and antipyretic treatments with mortality of critically ill patients with and without sepsis: multi-centered prospective observational study [J].

Lee, Byung Ho ;

Inui, Daisuke ;

Suh, Gee Young ;

Kim, Jae Yeol ;

Kwon, Jae Young ;

Park, Jisook ;

Tada, Keiichi ;

Tanaka, Keiji ;

Ietsugu, Kenichi ;

Uehara, Kenji ;

Dote, Kentaro ;

Tajimi, Kimitaka ;

Morita, Kiyoshi ;

Matsuo, Koichi ;

Hoshino, Koji ;

Hosokawa, Koji ;

Lee, Kook Hyun ;

Lee, Kyoung Min ;

Takatori, Makoto ;

Nishimura, Masaji ;

Sanui, Masamitsu ;

Ito, Masanori ;

Egi, Moritoki ;

Honda, Naofumi ;

Okayama, Naoko ;

Shime, Nobuaki ;

Tsuruta, Ryosuke ;

Nogami, Satoshi ;

Yoon, Seok-Hwa ;

Fujitani, Shigeki ;

Koh, Shin Ok ;

Takeda, Shinhiro ;

Saito, Shinsuke ;

Hong, Sung Jin ;

Yamamoto, Takeshi ;

Yokoyama, Takeshi ;

Yamaguchi, Takuhiro ;

Nishiyama, Tomoki ;

Igarashi, Toshiko ;

Kakihana, Yasuyuki ;

Koh, Younsuck .

CRITICAL CARE, 2012, 16 (01)

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