Granulomatous Inflammation of Liver Mimicking Malignancy on 68Ga-FAPI PET/CT

被引：0

作者：

Araz, Mine ^{[1
]}

Dursun, Ecenur ^{[1
]}

Mesci, Irem ^{[1
]}

Konca, Can ^{[2
]}

Soydal, Cigdem ^{[1
]}

Ozkan, Elgin ^{[1
]}

Kir, Kemal Metin ^{[1
]}

Kucuk, Nuriye Ozlem ^{[1
]}

机构：

[1] Ankara Univ, Med Sch, Dept Nucl Med, Ankara, Turkiye

[2] Ankara Univ, Med Sch, Dept Surg, Ankara, Turkiye

来源：

CLINICAL NUCLEAR MEDICINE | 2025年 / 50卷 / 07期

关键词：

Ga-68-FAPI; PET/CT; liver sarcoidosis; granulomatous inflammation;

D O I：

10.1097/RLU.0000000000005860

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Ga-68-FAPI has emerged as an alternative tracer for tumor imaging, as FAP is expressed in >90% of epithelial cancers. Although promising data on this new radiotracer are increasing, false-positive results due to nonmalignant diseases with FAP uptake are also reported (for instance, chronic inflammation, arthritis, and fibrosis). In this case, we demonstrated Ga-68-FAPI PET/CT involvement in a patient diagnosed with hepatic sarcoidosis.

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收藏

页码：E421 / E422

页数：2

相关论文

共 9 条

[1] Clinical application of 18F-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography in breast cancer [J].

Bernsdorf, M. ;

Graff, J. .

CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING, 2014, 34 (06) :426-433

[2] FAP and FAPI-PET/CT in Malignant and Non-Malignant Diseases: A Perfect Symbiosis? [J].

Dendl, Katharina ;

Koerber, Stefan A. ;

Kratochwil, Clemens ;

Cardinale, Jens ;

Finck, Rebecca ;

Dabir, Mardjan ;

Novruzov, Emil ;

Watabe, Tadashi ;

Kramer, Vasko ;

Choyke, Peter L. ;

Haberkorn, Uwe ;

Giesel, Frederik L. .

CANCERS, 2021, 13 (19)

[3] Superiority of 68Ga-FAPI PET/CT scan in detecting additional lesions compared to 18FDG PET/CT scan in breast cancer [J].

Elboga, Umut ;

Sahin, Ertan ;

Kus, Tulay ;

Cayirli, Yusuf Burak ;

Aktas, Gokmen ;

Uzun, Evren ;

Cinkir, Havva Yesil ;

Teker, Fatih ;

Sever, Ozlem Nuray ;

Aytekin, Alper ;

Yilmaz, Latif ;

Aytekin, Aydin ;

Cimen, Ufuk ;

Mumcu, Vuslat ;

Kilbas, Benan ;

Celen, Y. Zeki .

ANNALS OF NUCLEAR MEDICINE, 2021, 35 (12) :1321-1331

[4] Pitfalls and Common Findings in 68Ga-FAPI PET: A Pictorial Analysis [J].

Kessler, Lukas ;

Ferdinandus, Justin ;

Hirmas, Nader ;

Zarrad, Fadi ;

Nader, Michael ;

Kersting, David ;

Weber, Manuel ;

Kazek, Sandra ;

Sraieb, Miriam ;

Hamacher, Rainer ;

Lueckerath, Katharina ;

Umutlu, Lale ;

Fendler, Wolfgang P. ;

Rischpler, Christoph .

JOURNAL OF NUCLEAR MEDICINE, 2022, 63 (06) :890-896

[5] 68Ga-FAPI-04 PET/CT, a new step in breast cancer imaging: a comparative pilot study with the 18F-FDG PET/CT [J].

Komek, Halil ;

Can, Canan ;

Guzel, Yunus ;

Oruc, Zeynep ;

Gundogan, Cihan ;

Yildirim, Ozgen Ahmet ;

Kaplan, Ihsan ;

Erdur, Erkan ;

Yildirim, Mehmet Serdar ;

Cakabay, Bahri .

ANNALS OF NUCLEAR MEDICINE, 2021, 35 (06) :744-752

[6] Targeting of activated fibroblasts for imaging and therapy [J].

Lindner, Thomas ;

Loktev, Anastasia ;

Giesel, Frederik ;

Kratochwil, Clemens ;

Altmann, Annette ;

Haberkorn, Uwe .

EJNMMI RADIOPHARMACY AND CHEMISTRY, 2019, 4 (01)

[7] Limitations and Pitfalls of FDG-PET/CT in Infection and Inflammation [J].

Pijl, Jordy P. ;

Nienhuis, Pieter H. ;

Kwee, Thomas C. ;

Glaudemans, Andor W. J. M. ;

Slart, Riemer H. J. A. ;

Gormsen, Lars C. .

SEMINARS IN NUCLEAR MEDICINE, 2021, 51 (06) :633-645

[8] Pro-tumorigenic roles of fibroblast activation protein in cancer: back to the basics [J].

Pure, Ellen ;

Blomberg, Rachel .

ONCOGENE, 2018, 37 (32) :4343-4357

[9] 68Ga-FAPI Versus 18F-FDG PET/CT in Evaluating Newly Diagnosed Breast Cancer Patients A Head-to-Head Comparative Study [J].

Zheng, Shan ;

Lin, Junyu ;

Zhu, Youzhi ;

Chen, Yun ;

Zhang, Jiaying ;

Chen, Xiangjin ;

Miao, Weibing .

CLINICAL NUCLEAR MEDICINE, 2023, 48 (03) :E104-E109