Hepatic Langerhans cell histiocytosis: Report of a rare case

被引：0

作者：

Yao, Renling ^{[1
,2
]}

Chen, Jun ^{[3
]}

Li, Jie ^{[1
,2
]}

机构：

[1] Nanjing Univ, Nanjing Drum Tower Hosp, Affiliated Hosp,Med Sch, Dept Infect Dis, Nanjing, Jiangsu, Peoples R China

[2] Nanjing Univ, Inst Viruses & Infect Dis, Jiangsu, Peoples R China

[3] Nanjing Univ, Nanjing Drum Tower Hosp, Affiliated Hosp, Dept Pathol,Med Sch, Nanjing, Jiangsu, Peoples R China

来源：

HUMAN PATHOLOGY REPORTS | 2023年 / 34卷

关键词：

Langerhans cell histiocytosis; Langerin; CD1a; LIVER;

D O I：

10.1016/j.hpr.2023.300723

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Langerhans cell histiocytosis (LCH) is a rare neoplastic disease characterized by abnormal proliferation of Langerhans cells infiltrating various organs, resulting in organ dysfunction. In some patients, the BRAFV600E mutation can be detected. Histopathology reveals a substantial proliferation of Langerhans cells, contributing significantly to the diagnosis of LCH. Clinical manifestations vary depending on the affected tissues or organs. LCH occurs less frequently in adults than in children, and clinicians often lack sufficient awareness of this disease, making it susceptible to misdiagnosis. In this report, a case of liver injury caused by Langerhans cell invasion is presented, as confirmed by a liver biopsy in adults.

引用

页数：4

共 19 条

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