ACT on Vaping: Pilot Randomized Controlled Trial of a Novel Digital Health App With Text Messaging for Young Adult Vaping Cessation

被引：0

作者：

Heffner, Jaimee L. ^{[1
]}

Baker, Kelsey ^{[1
]}

Georgiou, Katerina ^{[2
]}

Graham, Amanda L. ^{[3
]}

Kelly, Megan M. ^{[4
]}

Konstantinou, Pinelopi ^{[2
,5
,6
]}

Lamprou, Eleana ^{[2
]}

Lele, Chinmaya ^{[7
]}

Lok, Kathleen Z. ^{[8
]}

Orzechowski, Maria ^{[9
]}

Ruiz, Raymond A. ^{[10
,11
]}

Serfozo, Edit ^{[1
]}

Karekla, Maria ^{[2
]}

机构：

[1] Fred Hutchinson Canc Ctr, Seattle, WA USA

[2] Univ Cyprus, Nicosia, Cyprus

[3] Truth Initiat, Innovat Ctr, Washington, DC USA

[4] Univ Massachusetts, Chan Med Sch, Worcester, MA USA

[5] Cyprus Univ Technol, Limassol, Cyprus

[6] UCLan Cyprus, Larnax, Cyprus

[7] Robert Morris Univ, Pittsburgh, PA USA

[8] Univ Michigan, Law Sch, Ann Arbor, MI USA

[9] Roosevelt Univ, Chicago, IL USA

[10] Northwestern Univ, Feinberg Sch Med, Chicago, IL USA

[11] Inst Sexual & Gender Minor Hlth & Wellbeing, Chicago, IL USA

来源：

NICOTINE & TOBACCO RESEARCH | 2025年

基金：

美国国家卫生研究院;

关键词：

COMMITMENT THERAPY; ACCEPTANCE; READINESS; QUIT; MODEL;

D O I：

10.1093/ntr/ntaf112

中图分类号：

R194 [卫生标准、卫生检查、医药管理];

学科分类号：

摘要：

Background There is no published evidence to support the efficacy of any digital vaping cessation program for young adults (YAs) at differing levels of readiness to quit. In this pilot randomized controlled trial, we evaluated the preliminary acceptability and efficacy of a program for vaping cessation based on acceptance and commitment therapy (ACT on Vaping), delivered via a smartphone app and text messaging.Methods YAs aged 18-30 (n = 61) were randomized 1:1 to ACT on Vaping (n = 31) or incentivized text message control (n = 30). Outcome data were collected at 3 months post-randomization. Results were compared against a priori benchmarks for acceptability (satisfaction of >= 3.5 on 5-point scale) and efficacy relative to control (meeting at least one of three): >= 1-point difference in Contemplation Ladder change scores; >= 5 percentage difference in 24-hour quit attempts, >= 5 percentage difference in cotinine-confirmed 30-day point prevalence abstinence (PPA) from all non-therapeutic nicotine/tobacco.Results Satisfaction with ACT on Vaping averaged 3.8, exceeding the acceptability benchmark. A higher proportion of participants in the ACT on Vaping arm reported a 24-hour quit attempt (87.5% vs. 75.9%), exceeding the efficacy benchmark. Both changes in quit readiness (+0.96 in ACT on Vaping vs. +0.72 in control) and cotinine-confirmed 30-day PPA (4.2% in ACT on Vaping vs. 0% in control) were descriptively higher for ACT on Vaping but did not reach the benchmark level for efficacy.Conclusions ACT on Vaping had promising acceptability and preliminary efficacy. A fully powered trial of ACT on Vaping is warranted to evaluate its efficacy.Implications Digital interventions are a promising yet under-researched approach for reaching and supporting YAs to quit vaping. This proof-of-concept pilot randomized controlled trial evaluated a novel mobile health application and associated text messaging program (ACT on Vaping) for young adult vaping cessation and found preliminary evidence for acceptability and efficacy relative to an incentivized text message control arm, warranting evaluation in a fully powered trial as a next step.Trial registration NCT05897242

引用

页数：11

共 40 条

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