AN EFFICIENT COPPER CATALYZEDSYNTHESIS OF 2-METHOXY-3-(1H-1,2,3- TRIAZOL-1-YL) METHYL)QUINOXALINES UNDER CLICK CONDITIONS

被引：0

作者：

Kethireddy, Shashikala ^{[1
]}

Syeda, Asrabanu ^{[2
]}

Vudari, Balaraju ^{[3
]}

Bommera, Ravi Kumar ^{[4
]}

Eppakayala, Laxminarayana ^{[3
]}

机构：

[1] Geethanjali Coll Engn & Technol, Hyderabad 501301, Telangana, India

[2] Jazan Univ, Coll Sci, Dept Phys Sci, Chem Div, POB 114, Jazan 45142, Saudi Arabia

[3] Sreenidhi Inst Sci & Technol Autonomous, Ghatkesar 501301, Telangana, India

[4] Sri Nicholas FineChem Labs, Hyderabad 500037, Telangana, India

来源：

HETEROCYCLIC LETTERS | 2024年 / 14卷 / 01期

关键词：

Click chemistry; quinoxalines; cycloaddition; dipole; dipolarophile; 1,2,3 triazoles; 1,2,3-TRIAZOLES; CYCLOADDITION; AZIDES;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

In order to synthesize a novel heterocyclic compound with quinoxaline and 1,2,3 triazole moieties containing potential biological activities, we carried out Huisgen type of 1,3 dipolar cycloaddition where 2-azido methyl quinoxaline and trimethyl silyl acetylene are used as dipole and dipolarophile respectively. To make the reaction more feasible, CuSO4.5H2O is used as a catalyst and sodium ascorbate was used as a reducing agent. Targeted products were characterized by IR, NMR, and Mass spectroscopic methods.

引用

页码：13 / 16

页数：4

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