Can 99mTc-PSMA SPECT/CT Presenting Mirror Image of 68Ga-PSMA PET/CT Be Used for Response Assessment to 177Lu-PSMA in Metastatic Castration-Resistant Prostate Cancer?

被引：0
作者：
Hooda, Monika [1 ]
Kumar, Suraj [1 ]
Prashar, Sarika [1 ]
Mavuduru, Ravimohan [2 ]
Singh, Baljinder [1 ]
机构：
[1] Postgrad Inst Med Educ & Res PGIMER, Dept Nucl Med, Chandigarh, India
[2] Postgrad Inst Med Educ & Res PGIMER, Dept Urol, Chandigarh, India
来源：
CLINICAL NUCLEAR MEDICINE | 2025年 / 50卷 / 08期
关键词：
Tc-99m-PSMA SPECT/CT; 68Ga-PSMA PET/CT; prostate cancer; 177Lu-PSMA; response assessment;
D O I：
10.1097/RLU.0000000000005754
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
A 69-year-old man, with a known case of metastatic castration-resistant prostate cancer (mCRPC) underwent Ga-68-PSMA PET/CT and Tc-99m-PSMA for evaluation of disease burden and response assessment to Lu-177-PSMA therapy. Tc-99m-PSMA provided a mirror image of Ga-68-PSMA. This suggests the potential of Tc-99m-PSMA SPECT/CT for disease evaluation and response assessment to PSMA-based radioligand therapies in advanced-stage mCRPC patients, especially when 68Ga-PSMA PET/CT is not available.
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页码：802 / 803
页数：2
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