Dialogue between programmed cell death and psoriasis

被引：0

作者：

Tian, Jun ^{[1
]}

Zhang, Lei ^{[1
]}

Yang, Li ^{[1
]}

机构：

[1] Shaanxi Prov Peoples Hosp, Dept Dermatol, 256 West Youyi Rd, Xian 710068, Peoples R China

来源：

POSTEPY DERMATOLOGII I ALERGOLOGII | 2025年 / 42卷 / 01期

关键词：

psoriasis; programmed cell death; apoptosis; ferroptosis; pyroptosis; autophagy; INFLAMMATORY RESPONSES; AUTOPHAGY; EXPRESSION; KERATINOCYTE; APOPTOSIS; METHOTREXATE; FERROPTOSIS; MECHANISMS; PYROPTOSIS; RECEPTOR;

D O I：

10.5114/ada.2024.147195

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Psoriasis is a chronic inflammatory skin condition, associated with both physical and psychological burden. The aetiology of psoriasis is not fully understood. Physiologically programmed cell death (PCD) pathways are crucial for maintaining organismal homeostasis. Several investigations have highlighted the link between dysregulated PCD and the initiation of psoriasis. This review aims to outline various forms of programmed cell death pathways, encompassing the psoriasis distinctive features, triggers, implications in psoriasis pathogenesis, and therapeutic opportunities. It aspires to offer a comprehensive exploration of the role of programmed cell death in the context of psoriasis, providing a rational framework for further investigation and potential therapeutic interventions.

引用

页码：13 / 20

页数：8

共 91 条

[1] Emerging connectivity of programmed cell death pathways and its physiological implications [J].

Bedoui, Sammy ;

Herold, Marco J. ;

Strasser, Andreas .

NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2020, 21 (11) :678-695

[2] Pyroptosis: host cell death and inflammation [J].

Bergsbaken, Tessa ;

Fink, Susan L. ;

Cookson, Brad T. .

NATURE REVIEWS MICROBIOLOGY, 2009, 7 (02) :99-109

[3] Methotrexate suppresses psoriatic skin inflammation by inhibiting muropeptide transporter SLC46A2 activity [J].

Bharadwaj, Ravi ;

Lusi, Christina F. ;

Mashayekh, Siavash ;

Nagar, Abhinit ;

Subbarao, Malireddi ;

Kane, Griffin I. ;

Wodzanowski, Kimberly A. ;

Brown, Ashley R. ;

Okuda, Kendi ;

Monahan, Amanda ;

Paik, Donggi ;

Nandy, Anubhab ;

Anonick, Madison, V ;

Goldman, William E. ;

Kanneganti, Thirumala-Devi ;

Orzalli, Megan H. ;

Grimes, Catherine Leimkuhler ;

Atukorale, Prabhani U. ;

Silverman, Neal .

IMMUNITY, 2023, 56 (05) :998-+

[4]

Billman ZP, 2024, ELIFE, V12, DOI [10.7554/eLife.92362, 10.7554/eLife.92362.4]

[5] Psoriasis [J].

Boehncke, Wolf-Henning ;

Schoen, Michael P. .

LANCET, 2015, 386 (9997) :983-994

[6] The IL-17 Family of Cytokines in Psoriasis: IL-17A and Beyond [J].

Brembilla, Nicolo Costantino ;

Senra, Luisa ;

Boehncke, Wolf-Henning .

FRONTIERS IN IMMUNOLOGY, 2018, 9

[7] The gasdermins, a protein family executing cell death and inflammation [J].

Broz, Petr ;

Pelegrin, Pablo ;

Shao, Feng .

NATURE REVIEWS IMMUNOLOGY, 2020, 20 (03) :143-157

[8] Gasdermin D in pyroptosis [J].

Burdette, Brandon E. ;

Esparza, Ashley N. ;

Zhu, Hua ;

Wang, Shanzhi .

ACTA PHARMACEUTICA SINICA B, 2021, 11 (09) :2768-2782

[9] UNC51-like kinase 1, autophagic regulator and cancer therapeutic target [J].

Chen, Y. ;

He, J. ;

Tian, M. ;

Zhang, S. -Y. ;

Guo, M. -R. ;

Kasimu, R. ;

Wang, J. -H. ;

Ouyang, L. .

CELL PROLIFERATION, 2014, 47 (06) :494-505

[10] Chlorquinaldol inhibits the activation of nucleotide-binding oligomerization domain-like receptor family pyrin domain-containing protein 3 inflammasome and ameliorates imiquimod-induced psoriasis-like dermatitis in mice [J].

Chen, Yanhong ;

Chen, Xiuhui ;

Liang, Shuli ;

Ou, Yitao ;

Lin, Geng ;

Hua, Lei ;

Wu, Xinyi ;

Zhou, Yinghua ;

Liu, Zhuorong ;

Cai, Haowei ;

Yang, Zhongjin ;

Hu, Wenhui ;

Sun, Ping .

CHEMICO-BIOLOGICAL INTERACTIONS, 2022, 365

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