Innovative electrochemical biosensors for tuberculosis detection

被引：0

作者：

Sadeghi, Mohammad Hassan ^{[1
]}

Radmehr, Safa ^{[2
]}

Mohagheghzadeh, Neda ^{[3
]}

Fathi, Javad ^{[3
]}

Malekzadegan, Yalda ^{[4
]}

Moghadam, Hesam Zendehdel ^{[5
]}

机构：

[1] Zahedan Univ Med Sci, Sch Med, Sistanbaluchestan, Iran

[2] Ahvaz Jundishapur Univ Med Sci, Hlth Res Inst, Thalassemia & Hemoglobinopathy Res Ctr, Ahvaz, Iran

[3] Shiraz Univ Med Sci, Sch Med, Dept Bacteriol & Virol, Shiraz, Iran

[4] Bushehr Univ Med Sci, Sch Med, Dept Microbiol & Parasitol, Bushehr, Iran

[5] Iranian Acad Ctr Educ Culture & Res, Res & Technol Dept, Kerman Branch, Tehran, Iran

来源：

CLINICA CHIMICA ACTA | 2025年 / 574卷

关键词：

Tuberculosis; Electrochemical biosensors; Nanomaterials; Diagnostic tools; T-CELL RESPONSES; GAMMA-INDUCIBLE PROTEIN-10; EFFECTOR MEMORY PHENOTYPE; SPUTUM SMEAR MICROSCOPY; REAL-TIME PCR; MYCOBACTERIUM-TUBERCULOSIS; ACTIVE TUBERCULOSIS; TH17; CELLS; DISEASE; ASSAY;

D O I：

10.1016/j.cca.2025.120327

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Tuberculosis (TB) continues to pose a significant global health threat, highlighting the urgent need for the development of rapid, precise, and accessible diagnostic tools to effectively manage its transmission. Conventional diagnostic techniques, such as sputum microscopy and culture-based assays, face several drawbacks, including lengthy processing times, limited sensitivity, and the requirement for specialized laboratory facilities. In this landscape, electrochemical biosensors have emerged as promising alternatives, offering improved sensitivity, specificity, and rapid detection capabilities. This review presents a thorough overview of recent advancements in the development and application of innovative electrochemical biosensors for TB detection. It explores the integration of nanomaterials such as graphene, gold nanoparticles, and carbon nanotubes, focusing on their contributions to enhanced sensor performance in terms of signal amplification and biorecognition efficacy. By synthesizing current research and technological developments, this review emphasizes the considerable potential of electrochemical biosensors to transform TB diagnostics, ultimately assisting in better disease management and control strategies worldwide.

引用

页数：13

共 182 条

[1] Distinct Effector Memory CD4+ T Cell Signatures in Latent Mycobacterium tuberculosis Infection, BCG Vaccination and Clinically Resolved Tuberculosis [J].

Adekambi, Toidi ;

Ibegbu, Chris C. ;

Kalokhe, Ameeta S. ;

Yu, Tianwei ;

Ray, Susan M. ;

Rengarajan, Jyothi .

PLOS ONE, 2012, 7 (04)

[2] Rapid and label-free A2 peptide epitope decorated CoFe2O4-C60 nanocomposite-based electrochemical immunosensor for detecting Visceral Leishmaniasis [J].

Adu, Darko Kwabena ;

Nate, Zondi ;

Alake, John ;

Ike, Blessing Wisdom ;

Mahlalela, Mavela Cleopus ;

Mohite, Sachin Balaso ;

Mokoena, Sithabile ;

Chauhan, Ruchika ;

Karpoormath, Rajshekhar .

BIOELECTROCHEMISTRY, 2024, 157

[3] Identification of diagnostic markers for tuberculosis by proteomic fingerprinting of serum [J].

Agranoff, Dan ;

Fernandez-Reyes, Delmiro ;

Papadopoulos, Marios C. ;

Rojas, Sergio A. ;

Herbster, Mark ;

Loosemore, Alison ;

Tarelli, Edward ;

Sheldon, Jo ;

Schwenk, Achim ;

Pollak, Richard ;

Rayner, Charlotte F. J. ;

Krishna, Sarjeev .

LANCET, 2006, 368 (9540) :1012-1021

[4] Heme Oxygenase-1 Regulation of Matrix Metalloproteinase-1 Expression Underlies Distinct Disease Profiles in Tuberculosis [J].

Andrade, Bruno B. ;

Kumar, Nathella Pavan ;

Amaral, Eduardo P. ;

Riteau, Nicolas ;

Mayer-Barber, Katrin D. ;

Tosh, Kevin W. ;

Maier, Nolan ;

Conceicao, Elisabete L. ;

Kubler, Andre ;

Sridhar, Rathinam ;

Banurekha, Vaithilingam V. ;

Jawahar, Mohideen S. ;

Barbosa, Theolis ;

Manganiello, Vincent C. ;

Moss, Joel ;

Fontana, Joseph R. ;

Marciano, Beatriz E. ;

Sampaio, Elizabeth P. ;

Olivier, Kenneth N. ;

Holland, Steven M. ;

Jackson, Sharon H. ;

Moayeri, Mahtab ;

Leppla, Stephen ;

Sereti, Irini ;

Barber, Daniel L. ;

Nutman, Thomas B. ;

Babu, Subash ;

Sher, Alan .

JOURNAL OF IMMUNOLOGY, 2015, 195 (06) :2763-2773

[5] Plasma Heme Oxygenase-1 Levels Distinguish Latent or Successfully Treated Human Tuberculosis from Active Disease [J].

Andrade, Bruno B. ;

Kumar, Nathella Pavan ;

Mayer-Barber, Katrin D. ;

Barber, Daniel L. ;

Sridhar, Rathinam ;

Rekha, Vaithilingam V. Banu ;

Jawahar, Mohideen S. ;

Nutman, Thomas B. ;

Sher, Alan ;

Babu, Subash .

PLOS ONE, 2013, 8 (05)

[6] Transcriptional Profile of Tuberculosis Antigen-Specific T Cells Reveals Novel Multifunctional Features [J].

Arlehamn, Cecilia Lindestam ;

Seumois, Gregory ;

Gerasimova, Anna ;

Huang, Charlie ;

Fu, Zheng ;

Yue, Xiaojing ;

Sette, Alessandro ;

Vijayanand, Pandurangan ;

Peters, Bjoern .

JOURNAL OF IMMUNOLOGY, 2014, 193 (06) :2931-2940

[7] Aptasensor for the Detection of Mycobacterium tuberculosis in Sputum Utilising CFP10-ESAT6 Protein as a Selective Biomarker [J].

Azmi, Umi Zulaikha Mohd ;

Yusof, Nor Azah ;

Abdullah, Jaafar ;

Mohammad, Faruq ;

Ahmad, Shahrul Ainliah Alang ;

Suraiya, Siti ;

Raston, Nurul Hanun Ahmad ;

Faudzi, Fatin Nabilah Mohd ;

Khiste, Sachin K. ;

Al-Lohedan, Hamad A. .

NANOMATERIALS, 2021, 11 (09)

[8] IFN-γ-inducible protein 10 and pentraxin 3 plasma levels are tools for monitoring inflammation and disease activity in Mycobacterium tuberculosis infection [J].

Azzurri, A ;

Sow, OY ;

Amedei, A ;

Bah, B ;

Diallo, S ;

Peri, G ;

Benagiano, M ;

D'Elios, MM ;

Mantovani, A ;

Del Prete, G .

MICROBES AND INFECTION, 2005, 7 (01) :1-8

[9] First independent evaluation of QuantiFERON-TB Plus performance [J].

Barcellini, Lucia ;

Borroni, Emanuele ;

Brown, James ;

Brunetti, Enrico ;

Codecasa, Luigi ;

Cugnata, Federica ;

Dal Monte, Paola ;

Di Serio, Clelia ;

Goletti, Delia ;

Lombardi, Giulia ;

Lipman, Marc ;

Rancoita, Paola M. V. ;

Tadolini, Marina ;

Cirillo, Daniela M. .

EUROPEAN RESPIRATORY JOURNAL, 2016, 47 (05) :1587-1590

[10] Tuberculosis Diagnosis: Current, Ongoing, and Future Approaches [J].

Bartolomeu-Goncalves, Guilherme ;

Souza, Joyce Marinho de ;

Fernandes, Bruna Terci ;

Spoladori, Lais Fernanda Almeida ;

Correia, Guilherme Ferreira ;

de Castro, Isabela Madeira ;

Borges, Paulo Henrique Guilherme ;

Silva-Rodrigues, Gislaine ;

Tavares, Eliandro Reis ;

Yamauchi, Lucy Megumi ;

Pelisson, Marsileni ;

Perugini, Marcia Regina Eches ;

Yamada-Ogatta, Sueli Fumie .

DISEASES, 2024, 12 (09)

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