Meta-analysis of outcomes in patients developing acute kidney injury after endovascular aortic repair for Stanford type B aortic dissection

Thoracic endovascular aortic repair (TEVAR) is recommended for patients with Stanford type B aortic dissection at risk of aneurysm rupture or enlargement. Although studies suggest that postoperative acute kidney injury (AKI) may worsen outcomes and increase mortality, its specific impact in TEVAR-treated patients remains uncertain. To address this, a meta-analysis was conducted comparing outcomes in patients who developed AKI post-TEVAR versus those who did not. A comprehensive literature search identified three studies involving 1091 patients, with 234 in the AKI group and 857 in the non-AKI group. Relative risks (RRs) were pooled using random-effects models, with statistical significance set at P less than 0.05. The findings indicated that AKI significantly increased the risk of in-hospital mortality (RR: 5.31, P < 0.0001), stroke (RR: 2.33, P = 0.0046), and dialysis requirement (RR: 18.43, P = 0.0008). These results underscore the need for early identification of AKI risk factors in patients with TEVAR and further research to explore its long-term effects.