Predicting response speed and age from task-evoked effective connectivity

被引：0

作者：

Zhang, Shufei ^{[1
,2
]}

Jung, Kyesam ^{[1
,2
]}

Langner, Robert ^{[1
,2
]}

Florin, Esther ^{[3
]}

Eickhoff, Simon B. ^{[1
,2
]}

Popovych, Oleksandr V. ^{[1
,2
]}

机构：

[1] Res Ctr Julich, Inst Neurosci & Med Brain & Behav INM 7, Julich, Germany

[2] Heinrich Heine Univ Dusseldorf, Inst Syst Neurosci, Med Fac, Dusseldorf, Germany

[3] Heinrich Heine Univ Dusseldorf, Inst Clin Neurosci & Med Psychol, Med Fac, Dsseldorf, Germany

来源：

NETWORK NEUROSCIENCE | 2025年 / 9卷 / 02期

关键词：

Task fMRI; Dynamic causal modeling; Analytic flexibility; Machine learning; Brain-based prediction; Stimulus-response compatibility; Functional connectivity; EVENT-RELATED FMRI; FUNCTIONAL CONNECTIVITY; INDIVIDUAL-DIFFERENCES; NETWORK CONNECTIVITY; WORKING-MEMORY; BRAIN; COMPATIBILITY; SELECTION; STIMULUS; STATE;

D O I：

10.1162/netn_a_00447

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

We investigated how brain task-evoked effective connectivity (EC) can predict individual differences in behavior and age. We examined two types of EC: intrinsic EC (calculated at baseline) and task-modulated EC (induced by experimental conditions) calculated by dynamic causal modeling across various data processing conditions. We found that the task-modulated EC outperformed intrinsic EC in predicting reaction time measured during a stimulus-response task, while both EC types performed similarly in age prediction. Our findings may suggest that different EC types could capture distinct phenotypic traits, with performance influenced by data processing and modeling choices. This evaluation may further promote the application of model-based approaches to behavior prediction from brain connectivity and enhance our understanding of the impact of data processing on the prediction results.

引用

页码：591 / 614

页数：24

共 71 条

[1] Value-driven attentional priority signals in human basal ganglia and visual cortex [J].

Anderson, Brian A. ;

Laurent, Patryk A. ;

Yantis, Steven .

BRAIN RESEARCH, 2014, 1587 :88-96

[2] Cortical signatures of precision grip force control in children, adolescents, and adults [J].

Beck, Mikkel Malling ;

Spedden, Meaghan Elizabeth ;

Dietz, Martin Jensen ;

Karabanov, Anke Ninija ;

Christensen, Mark Schram ;

Lundbye-Jensen, Jesper .

ELIFE, 2021, 10

[3] Toward discovery science of human brain function [J].

Biswal, Bharat B. ;

Mennes, Maarten ;

Zuo, Xi-Nian ;

Gohel, Suril ;

Kelly, Clare ;

Smith, Steve M. ;

Beckmann, Christian F. ;

Adelstein, Jonathan S. ;

Buckner, Randy L. ;

Colcombe, Stan ;

Dogonowski, Anne-Marie ;

Ernst, Monique ;

Fair, Damien ;

Hampson, Michelle ;

Hoptman, Matthew J. ;

Hyde, James S. ;

Kiviniemi, Vesa J. ;

Kotter, Rolf ;

Li, Shi-Jiang ;

Lin, Ching-Po ;

Lowe, Mark J. ;

Mackay, Clare ;

Madden, David J. ;

Madsen, Kristoffer H. ;

Margulies, Daniel S. ;

Mayberg, Helen S. ;

McMahon, Katie ;

Monk, Christopher S. ;

Mostofsky, Stewart H. ;

Nagel, Bonnie J. ;

Pekar, James J. ;

Peltier, Scott J. ;

Petersen, Steven E. ;

Riedl, Valentin ;

Rombouts, Serge A. R. B. ;

Rypma, Bart ;

Schlaggar, Bradley L. ;

Schmidt, Sein ;

Seidler, Rachael D. ;

Siegle, Greg J. ;

Sorg, Christian ;

Teng, Gao-Jun ;

Veijola, Juha ;

Villringer, Arno ;

Walter, Martin ;

Wang, Lihong ;

Weng, Xu-Chu ;

Whitfield-Gabrieli, Susan ;

Williamson, Peter ;

Windischberger, Christian .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2010, 107 (10) :4734-4739

[4] Age-related changes in causal interactions between cortical motor regions during hand grip [J].

Boudrias, Marie-Helene ;

Goncalves, Carla Sa ;

Penny, Will D. ;

Park, Chang-hyun ;

Talelli, Penelope ;

Ward, Nick S. .

NEUROIMAGE, 2012, 59 (04) :3398-3405

[5] Generative Embedding for Model-Based Classification of fMRI Data [J].

Brodersen, Kay H. ;

Schofield, Thomas M. ;

Leff, Alexander P. ;

Ong, Cheng Soon ;

Lomakina, Ekaterina I. ;

Buhmann, Joachim M. ;

Stephan, Klaas E. .

PLOS COMPUTATIONAL BIOLOGY, 2011, 7 (06)

[6] Opportunities and limitations of intrinsic functional connectivity MRI [J].

Buckner, Randy L. ;

Krienen, Fenna M. ;

Yeo, B. T. Thomas .

NATURE NEUROSCIENCE, 2013, 16 (07) :832-837

[7] Does erotic stimulus presentation design affect brain activation patterns?: Event-related vs. blocked fMRI designs [J].

Buehler, Mira ;

Vollstaedt-Klein, Sabine ;

Klemen, Jane ;

Smolka, Michael N. .

BEHAVIORAL AND BRAIN FUNCTIONS, 2008, 4 (1)

[8] Feature selection in machine learning: A new perspective [J].

Cai, Jie ;

Luo, Jiawei ;

Wang, Shulin ;

Yang, Sheng .

NEUROCOMPUTING, 2018, 300 :70-79

[9] Studying variability in human brain aging in a population-based German cohort-rationale and design of 1000 BRAINS [J].

Caspers, Svenja ;

Moebus, Susanne ;

Lux, Silke ;

Pundt, Noreen ;

Schuetz, Holger ;

Muehleisen, Thomas W. ;

Gras, Vincent ;

Eickhoff, Simon B. ;

Romanzetti, Sandro ;

Stoecker, Tony ;

Stirnberg, Ruediger ;

Kirlangic, Mehmet E. ;

Minnerop, Martina ;

Pieperhoff, Peter ;

Moedder, Ulrich ;

Das, Samir ;

Evans, Alan C. ;

Joeckel, Karl-Heinz ;

Erbel, Raimund ;

Cichon, Sven ;

Noethen, Markus M. ;

Sturma, Dieter ;

Bauer, Andreas ;

Shah, N. Jon ;

Zilles, Karl ;

Amunts, Katrin .

FRONTIERS IN AGING NEUROSCIENCE, 2014, 6

[10] Dynamic interactions in the fronto-parietal network during a manual stimulus-response compatibility task [J].

Cieslik, Edna C. ;

Zilles, Karl ;

Grefkes, Christian ;

Eickhoff, Simon B. .

NEUROIMAGE, 2011, 58 (03) :860-869

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