Intestinal Perforation Secondary to Bortezomib-Induced Autonomic Neuropathy

被引：0

作者：

Salas, Jose Antonio Sanchez ^{[1
]}

Belmonte, Maria Jose Moreno ^{[1
]}

Garcia, Andrea Poveda ^{[1
]}

Ruiz, Estela Ruiz ^{[1
]}

Espejo, Eva Soler ^{[1
]}

Perianes, Valentin Cabanas ^{[1
]}

Hernandez, Ana Maria Garcia ^{[1
]}

机构：

[1] Virgen Arrixaca Univ Hosp, Dept Hematol, Murcia, Spain

来源：

CLINICAL CASE REPORTS | 2025年 / 13卷 / 04期

关键词：

Bortezomib; Intestinal perforation; Intestinal Pseudo-obstruction; multiple myeloma; peripheral neuropathies; PARALYTIC ILEUS;

D O I：

10.1002/ccr3.70340

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

It is essential to evaluate both the patient's prior conditions and the severity of the current clinical presentation when deciding on BTZ toxicity management. It seems prudent to consider the permanent discontinuation of the drug in patients who have experienced at least grade 3 intestinal neuropathy and have structural abnormalities or other risk factors for intestinal perforation.Trial Registration: NCT03710603

引用

页数：4

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