Research Progress of Traditional Chinese Medicine in Adjuvant Treatment of Type 1 Diabetes

被引：0
作者：
Luo, Jian [1 ]
Hu, Fuli [1 ]
Jia, Zhuolin [1 ]
Zhu, Xiaoli [1 ]
Zhou, Ye [1 ]
Hu, Changhe [2 ]
Yu, Lingying [1 ]
Chen, Zhimin [1 ,3 ]
机构：
[1] Chengdu Univ Tradit Chinese Med, Sch Pharm, Sch Modern Chinese Med Ind, State Key Lab Southwestern Chinese Med Resources, Chengdu, Peoples R China
[2] Tradit Hosp Dachuan Cty Dazhou, Dazhou, Peoples R China
[3] Chengdu Univ Tradit Chinese Med, Pengzhou, Sichuan, Peoples R China
来源：
PHYTOTHERAPY RESEARCH | 2025年
关键词：
action mechanism; combination of traditional Chinese medicine with western medicine; traditional Chinese medicine; type; 1; diabetes; SALVIANOLIC ACID B; INSULIN-RESISTANCE; OXIDATIVE STRESS; LIUWEI DIHUANG; PORIA-COCOS; PPAR-GAMMA; INDUCED HYPERGLYCEMIA; GINSENOSIDE RB1; HERBAL MEDICINE; MOLECULAR-BASIS;
D O I：
10.1002/ptr.8514
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Type 1 diabetes (T1DM) is one of the most common chronic metabolic diseases in the world. Insulin replacement therapy and drug adjuvant therapy are the main means of modern medical treatment of T1DM; still, there are adverse reactions such as drug resistance, which seriously hinder the therapeutic effect. As a unique medical method in China, traditional Chinese medicine (TCM) has a significant effect on the treatment of T1DM. TCM therapy can reduce the symptoms of T1DM, prevent complications, improve insulin resistance, and promote insulin secretion. In recent years, the research field of TCM in the treatment of T1DM has made considerable progress. The research on the treatment of T1DM by Chinese herbal medicine, TCM prescription, acupuncture, and moxibustion shows good anti-T1DM effect and significantly improves the survival rate of patients. This article aims to summarize the methods of TCM in the treatment of T1DM, expounds on the mechanism of action in the treatment of T1DM, and discusses the limitations and opportunities of TCM in the treatment of T1DM.
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页数：37
相关论文
共 224 条
[41]   Metformin: update on mechanisms of action and repurposing potential [J].
Foretz, Marc ;
Guigas, Bruno ;
Viollet, Benoit .
NATURE REVIEWS ENDOCRINOLOGY, 2023, 19 (08) :460-476
[42]   Traditional Chinese medicine foot bath combined with acupoint massage for the treatment of diabetic peripheral neuropathy: A systematic review and meta-analysis of 31 RCTs [J].
Fu, Qinwei ;
Yang, Hui ;
Zhang, Lanzhi ;
Liu, Yang ;
Li, Xinrong ;
Dai, Menglin ;
Yang, Yepeng ;
Yang, Shasha ;
Xie, Yan ;
Liu, Ying ;
Fu, Li ;
Liu, Zhiqing ;
Zhang, Qinxiu .
DIABETES-METABOLISM RESEARCH AND REVIEWS, 2020, 36 (02)
[43]   The Yin and Yang of traditional Chinese and Western medicine [J].
Fu, Rao ;
Li, Jie ;
Yu, Huatao ;
Zhang, Yang ;
Xu, Zhihong ;
Martin, Cathie .
MEDICINAL RESEARCH REVIEWS, 2021, 41 (06) :3182-3200
[44]   Pleiotropic Actions of Aldehyde Reductase (AKR1A) [J].
Fujii, Junichi ;
Homma, Takujiro ;
Miyata, Satoshi ;
Takahashi, Motoko .
METABOLITES, 2021, 11 (06)
[45]   Ginsenoside Rg1 protects mice against streptozotocin-induced type 1 diabetic by modulating the NLRP3 and Keap1/Nrf2/HO-1 pathways [J].
Gao, Yan ;
Li, Juntong ;
Chu, Shifeng ;
Zhang, Zhao ;
Chen, Naihong ;
Li, Lin ;
Zhang, Lan .
EUROPEAN JOURNAL OF PHARMACOLOGY, 2020, 866
[46]  
Garcia-Vivas JM, 2014, J RES MED SCI, V19, P610
[47]   Natural α-Glucosidase and Protein Tyrosine Phosphatase 1B Inhibitors: A Source of Scaffold Molecules for Synthesis of New Multitarget Antidiabetic Drugs [J].
Genovese, Massimo ;
Nesi, Ilaria ;
Caselli, Anna ;
Paoli, Paolo .
MOLECULES, 2021, 26 (16)
[48]   Current understandings of the pathogenesis of type 1 diabetes: Genetics to environment [J].
Giwa, Adebola Matthew ;
Ahmed, Rizwan ;
Omidian, Zahra ;
Majety, Neha ;
Karakus, Kagan Ege ;
Omer, Sarah M. ;
Donner, Thomas ;
Hamad, Abdel Rahim A. .
WORLD JOURNAL OF DIABETES, 2020, 11 (01) :13-25
[49]   Hypoglycemic effect of astragaloside IV via modulating gut microbiota and regulating AMPK/SIRT1 and PI3K/AKT pathway [J].
Gong, Pin ;
Xiao, Xuyang ;
Wang, Shuang ;
Shi, Fuxiong ;
Liu, Ni ;
Chen, Xuefeng ;
Yang, Wenjuan ;
Wang, Lan ;
Chen, Fuxin .
JOURNAL OF ETHNOPHARMACOLOGY, 2021, 281
[50]  
[龚胜男 Gong Shengnan], 2021, [中华中医药杂志, China Journal of Traditional Chinese Medicine and Pharmacy], V36, P243
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