Safety and Current Status of the COVID-19 Vaccine among Patients with Breast cancer: A Cross-Sectional Study from China

被引：1

作者：

Zhang, Shaohua ^{[1
]}

Li, Jianbin ^{[1
]}

Xu, Ruonan ^{[2
]}

Chen, Qianjun ^{[3
]}

Sun, Gang ^{[4
]}

Lin, Ying ^{[5
]}

Jin, Feng ^{[6
]}

Liu, Xinlan ^{[7
]}

Fan, Zhimin ^{[8
]}

Chen, Yiding ^{[9
]}

Cao, Yali ^{[10
]}

Li, Xinzheng ^{[11
]}

Nie, Jianyun ^{[12
]}

Xu, Guiying ^{[13
]}

Wang, Xiaojia ^{[14
]}

Teng, Yuee ^{[15
]}

Sun, Tao ^{[16
]}

Liu, Hong ^{[17
]}

Luo, Jing ^{[18
]}

Geng, Cuizhi ^{[19
]}

Li, Man ^{[20
]}

Luo, Ting ^{[21
]}

Liu, Yinhua ^{[22
]}

Wang, Fu-Sheng ^{[2
]}

Jiang, Zefei ^{[1
]}

机构：

[1] Peoples Liberat Army Gen Hosp, Med Ctr 5, Dept Oncol, Beijing 100071, Peoples R China

[2] Chinese Peoples Liberat Army Gen Hosp, Med Ctr 5, Dept Infect Dis, Beijing 100039, Peoples R China

[3] Guangdong Prov Hosp Tradit Chinese Med, Dept Breast Canc, Guangzhou 510000, Peoples R China

[4] Xinjiang Med Univ, Canc Hosp, Dept Breast Head & Neck Surg, Urumqi 830011, Peoples R China

[5] Sun Yat Sen Univ, Affiliated Hosp 1, Dept Breast Surg, Guangzhou 510062, Peoples R China

[6] China Med Univ, Affiliated Hosp 1, Dept Breast Surg, Shenyang 110001, Peoples R China

[7] Ningxia Med Univ, Gen Hosp, Dept Oncol, Yinchuan 750003, Ningxia, Peoples R China

[8] First Hosp Jilin Univ, Dept Breast Surg, Changchun 130031, Peoples R China

[9] Zhejiang Univ, Affiliated Hosp 2, Med Coll, Dept Oncol Surg, Hangzhou 310009, Peoples R China

[10] Nanchang Third Hosp, Dept Oncol, Nanchang 330009, Peoples R China

[11] Shanxi Canc Hosp, Dept Breast Surg, Taiyuan 030013, Peoples R China

[12] Yunnan Canc Hosp, Dept Breast Surg, Kunming 650118, Peoples R China

[13] Jilin Canc Hosp, Dept Breast Surg, Changchun 130012, Peoples R China

[14] Univ Chinese Acad Sci, Canc Hosp, Dept Oncol, Hangzhou 310005, Peoples R China

[15] China Med Univ, Affiliated Hosp 1, Dept Oncol, Shenyang 110001, Peoples R China

[16] Liaoning Canc Hosp, Dept Oncol, Shenyang 110801, Peoples R China

[17] Tianjin Med Univ, Tumor Hosp, Dept Oncol, Tianjin 300060, Peoples R China

[18] Sichuan Prov Peoples Hosp, Sichuan Acad Med Sci, Chengdu, Peoples R China

[19] Hebei Med Univ, Hosp 4, Dept Breast Canc, Shijiazhuang 050011, Peoples R China

[20] Dalian Med Univ, Affiliated Hosp 2, Dept Oncol, Dalian 116050, Peoples R China

[21] Sichuan Univ, West China Hosp, Dept Head & Neck Tumor, Chengdu 610042, Peoples R China

[22] Peking Univ First Hosp, Dept Hematol, Beijing 100034, Peoples R China

来源：

INFECTIOUS DISEASES & IMMUNITY | 2023年 / 3卷 / 03期

关键词：

Breast cancer; COVID-19; vaccine; Safety;

D O I：

10.1097/ID9.0000000000000090

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

In this study, we aimed to explore the safety and vaccination coverage data of Chinese patients with breast cancer receiving coronavirus disease 2019 (COVID-19) vaccination. The patients were recruited from 41 hospitals across 20 Chinese provinces. The vaccination coverage was approximately 22.4%, and the frequency of total adverse events was 13.3% after the first dose and 9.9% after the second dose. The most frequent adverse reaction within 14 days of the first dose was local pain (5.7%). Unvaccinated patients were very likely to reject the vaccine rather than be hesitant in patients with old age (odds ratio [OR], 1.238; 95% confidence interval [CI], 1.101-1.391), chronic disease history (OR, 1.189; 95% CI, 1.057-1.337), and cancer relapse (OR, 1.398; 95% CI, 1.233-1.585). Of the unvaccinated patients with breast cancer, 54.1% opted to receive COVID-19 vaccines if more data were available. Considering the safety but low vaccination coverage for breast cancer, increased positive attitudes and acceptance toward COVID-19 vaccines are important.

引用

页码：127 / 131

页数：5

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