Association between long-term changes in obesity-related anthropometric indicators and the risk of type 2 diabetes mellitus in the older population

被引：0
作者：
Xu, Xiaomin [1 ]
Li, Lirong [1 ]
Chen, Fengmei [2 ]
Guo, Zhirong [3 ]
机构：
[1] Suzhou Vocat Hlth Coll, Dept Clin Med, Suzhou, Peoples R China
[2] Vocat Hlth Coll, Dept Publ Hlth, 28 Kehua Rd,High Tech Zone, Suzhou 215009, Jiangsu, Peoples R China
[3] Soochow Univ, Sch Publ Hlth, Dept Epidemiol, Suzhou, Peoples R China
来源：
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH | 2025年 / 53卷 / 06期
关键词：
Obesity; body mass index; waist circumference; waist-to-height ratio; type 2 diabetes mellitus; older population; BODY-MASS INDEX; TO-HEIGHT RATIO; WAIST CIRCUMFERENCE; ABDOMINAL OBESITY; CARDIOVASCULAR-DISEASE; WEIGHT; EPIDEMIOLOGY; ADIPOSITY; FAT;
D O I：
10.1177/03000605251348229
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Objective To investigate the association of long-term changes in body mass index, waist circumference, and waist-to-height ratio with the risk of type 2 diabetes mellitus in the older population.Methods We conducted a prospective cohort study in Jiangsu Province, China. Data from 593 participants who were aged >= 60 years were analyzed. The hazard ratios and 95% confidence intervals were estimated using the Cox proportional hazards model.Results Over a median follow-up period of 5.08 years, 70 participants (11.80%) developed type 2 diabetes mellitus. Compared with participants with persistently normal body mass index, waist circumference, and waist-to-height ratio, those in whom these parameters changed from normal to abnormal and those in whom these parameters were persistently abnormal had a significantly higher risk of type 2 diabetes mellitus, with adjusted hazard ratios of 2.11 (95% confidence interval: 1.05-4.26) and 2.37 (95% confidence interval: 1.21-4.63) for body mass index, 2.75 (95% confidence interval: 1.16-6.51) and 2.32 (95% confidence interval: 1.29-4.16) for waist circumference, and 2.24 (95% confidence interval: 1.14-5.91) and 4.11 (95% confidence interval: 2.21-7.68) for waist-to-height ratio, respectively.Conclusion Long-term changes in obesity-related anthropometric indicators are strongly associated with the risk of type 2 diabetes mellitus in the older population.
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页数：11
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