Recent advances in the chemistry of selenophenofurans and their analogues

The fusion of furan and selenophene in hybrid configurations results in four distinct structural types: condensed 1H,3H-selenopheno[3,4-c]furans, selenopheno[3,4-b]furans, selenopheno[2,3-b]furans, and selenopheno[3,2-b] furans. Despite their potential, no dedicated studies have exclusively explored this scaffold, which has primarily been employed as a versatile building block across various applications. The synthesis of selenophenofurans and their analogs can be achieved through diverse chemical approaches, including (i) selenation reactions, (ii) Suzuki-Miyaura coupling, (iii) Stille and Sonogashira coupling, and (iv) cyclization reactions, among other methods.