The Role of Osteoporosis in Total Hip Arthroplasty Periprosthetic Fractures and Current Management Strategies: a Review

Purpose of ReviewThis review provides a background on osteoporosis, describes the relationship between osteoporosis and periprosthetic fracture following total hip arthroplasty (THA), as well as to discusses current management strategies and future directions for improved patient outcomes.Recent FindingsPeriprosthetic fracture of the hip is among one of the most common reasons for revision following THA and occurs in 0.1-3.5% of individuals. Periprosthetic fractures come with significant cost, morbidity, and future mortality. Risks for periprosthetic fractures following THA include female sex, older age, rheumatoid arthritis, and osteoporosis. Recent works have demonstrated that osteoporosis plays an important role in the rising prevalence of periprosthetic fractures following THA.SummaryThis review characterizes the interplay between osteoporosis and periprosthetic hip fractures following THA with emphasis placed upon the pathophysiology of osteoporosis, the mechanisms by which osteoporosis promote periprosthetic fractures, management of such fractures, and the potential for future therapies.