Enhancing Outcomes in Transarterial Embolization for Late Postpancreatectomy Hemorrhage: A Comparison of N-Butyl Cyanoacrylate with Mixed Embolic Agents Versus Mixed Embolic Agents Alone

被引：0

作者：

Zhang, Heng ^{[1
,2
]}

Duan, Feng ^{[1
]}

Fu, Jin Xin ^{[1
]}

Zhang, Jin Long ^{[3
]}

Yuan, Bing ^{[1
]}

Wang, Yan ^{[1
]}

Yan, Jie Yu ^{[1
]}

Meng, Li Min ^{[4
]}

Li, Liang ^{[5
]}

Wang, Mao Qiang ^{[1
]}

机构：

[1] Chinese Peoples Liberat Army Gen Hosp, Med Sch Chinese PLA, Dept Intervent radiol, Beijing, Peoples R China

[2] Chinese Peoples Liberat Army Gen Hosp, Natl Clin Res Ctr Geriatr Dis, Med Ctr 2, Dept Radiol, Beijing, Peoples R China

[3] Capital Med Univ, Beijing Tongren Hosp, Dept Radiol, Beijing, Peoples R China

[4] Air Force Med Ctr PLA, Dept Med Imaging, Beijing, Peoples R China

[5] Bethune Int Peace Hosp, Dept Intervent, Shijiazhuang, Peoples R China

来源：

JOURNAL OF INVESTIGATIVE SURGERY | 2025年 / 38卷 / 01期

基金：

中国国家自然科学基金;

关键词：

Arterial bleeding; postoperative hemorrhage; interventional radiology; treatment outcome; TRANSCATHETER ARTERIAL EMBOLIZATION; EFFICACY;

D O I：

10.1080/08941939.2025.2488133

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

BackgroundThis study aimed to retrospectively compare the efficacy of transarterial embolization (TAE) with N-butyl cyanoacrylate (NBCA) and conventional agents (microcoils, polyvinyl alcohol [PVA], or gelatin sponge) in the treatment of patients with late postpancreatectomy hemorrhage (late-PPH).MethodsFrom June 2012 to June 2022, this retrospective study enrolled 130 consecutive patients who underwent TAE treatment due to late-PPH at one institution. Of these patients, 56 were treated with NBCA-mixed conventional agents (NBCA-MA group), and 74 were treated with mixed conventional agents alone (MA group). The patients' clinical characteristics and TAE details were gathered. The clinical outcomes in the two groups were compared. Using univariate and multivariate logistic regression analyses, prognostic factors were evaluated for clinical success and 30-day mortality rates.ResultsThe clinical success in the NBCA-MA group was 80.4% higher than that in the MA group (60.8%). Rebleeding was significantly more common in the MA group (29.7% vs. 8.9%). The 30-day mortality rate of the NBCA-MA group was lower than that of the MA group (16.1% vs. 33.8%). NBCA use was a significant prognostic factor associated with clinical success, while age and NBCA use were significant factors associated with the 30-day mortality rate.ConclusionIn conclusion, we found that TAE with NBCA is a safe and effective method for treating late-PPH.

引用

页数：7