Roflumilast reduces the number of lung adenocarcinomas, inflammation, and emphysema in a smoking-induced mouse model

被引：0

作者：

Kaori Sakurai ^{[1
]}

Shingo Nakayama ^{[1
]}

Shotaro Chubachi ^{[1
]}

Shiro Otake ^{[1
]}

Takashi Shimada ^{[1
]}

Hidehiro Irie ^{[1
]}

Akihiro Tsutsumi ^{[1
]}

Naofumi Kameyama ^{[1
]}

Ahmed E. Hegab ^{[2
]}

Masayuki Shimoda ^{[3
]}

Junko Hamamoto ^{[4
]}

Hideki Terai ^{[1
]}

Hiroyuki Yasuda ^{[1
]}

Yae Kanai ^{[1
]}

Koichi Fukunaga ^{[3
]}

机构：

[1] Keio University School of Medicine,Division of Pulmonary Medicine, Department of Internal Medicine

[2] International University of Health and Welfare,Medical Education Center, School of Medicine

[3] Keio University School of Medicine,Department of Pathology

[4] The Jikei University School of Medicine,Department of Pathology

来源：

关键词：

Chronic obstructive pulmonary disease; Lung neoplasm; PDE4 inhibitor; Smoking; Chemoprevention;

D O I：

10.1186/s12890-025-03730-w

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学科分类号：

摘要：

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