Inhibition of Farnesoid-x-receptor signaling during abdominal sepsis by dysbiosis exacerbates gut barrier dysfunction

被引:0
作者
Shuwen Qian [1 ]
Zehua Su [2 ]
Jiaqi Lin [7 ]
Qianhao Hou [2 ]
Xiaomei Wang [7 ]
Yuling Li [2 ]
Jieying Wang [7 ]
Changchun Huang [2 ]
Zetian Wang [7 ]
Francisco Javier Cubero [2 ]
Xiangrui Wang [3 ]
Lijun Liao [4 ]
机构
[1] Yangpu Hospital,Department of Anesthesiology and Pain Management, School of Medicine
[2] Tongji University,Department of Pain Management, School of Medicine
[3] Shanghai East Hospital,Department of Pharmacy, School of Medicine
[4] Tongji University,Clinical Center for Investigation, School of Medicine
[5] Ji’an Hospital,Department of Anesthesiology
[6] Shanghai East Hospital,Department of Immunology, Ophthalmology and ENT
[7] Tongji University,Institute of Pain Medicine, Shanghai East Hospital
[8] Renji Hospital,undefined
[9] Shanghai Jiao Tong University,undefined
[10] Ningbo First Hospital,undefined
[11] Complutense University School of Medicine,undefined
[12] School of medicine,undefined
[13] Tongji University,undefined
关键词
Sepsis; Gut microbiota; Myd88; FXR; FGF15; Probiotics; Bile acids;
D O I
10.1186/s12964-025-02224-w
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