Macrophage Notch1 drives septic cardiac dysfunction by impairing mitophagy and promoting NLRP3 activation

被引:0
|
作者
Yanjun Zheng [1 ]
Jingrong Lin [5 ]
Guoqing Wan [2 ]
Xuefeng Gu [1 ]
Jian Ma [1 ]
机构
[1] Shanghai University of Medicine and Health Sciences,Shanghai Key Laboratory of Molecular Imaging, Zhoupu Hospital
[2] Shanghai Jiao Tong University School of Medicine,Department of Hypertension, Ruijin Hospital, Shanghai Institute of Hypertension
[3] Shanghai Jiao Tong University School of Medicine Affiliated Sixth People’s Hospital,Department of Cardiology
[4] Shanghai Jiao Tong University Affiliated Sixth People’s Hospital,undefined
[5] Shanghai University of Medicine & Health Sciences Affiliated Zhoupu Hospital,undefined
关键词
Sepsis; Notch1; Mitophagy; Macrophages; NLRP3;
D O I
10.1186/s13062-025-00657-4
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