Rethinking the Use of Biologics in Inflammatory Bowel Disease Patients With Malignancy: Insights From the Treatment of Immune Checkpoint Inhibitor-Induced Colitis

被引：0
作者：
Lenti, Marco Vincenzo [1 ,2 ]
Santacroce, Giovanni [1 ,2 ]
Di Sabatino, Antonio [1 ,2 ]
机构：
[1] Univ Pavia, Dept Internal Med & Med Therapeut, Pavia, Italy
[2] San Matteo Hosp Fdn, Dept Internal Med, Pavia, Italy
来源：
INFLAMMATORY BOWEL DISEASES | 2025年
关键词：
biologics; cancer; immunotherapy; Crohn's disease; ulcerative colitis;
D O I：
10.1093/ibd/izaf065
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Managing inflammatory bowel disease in cancer patients is challenging due to concerns about biologics' effects on malignancy. Recent evidence suggests a low risk of cancer progression, but data gaps persist. Research on immune checkpoint inhibitor-induced colitis and biologic safety remains limited.
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