The study examined the influence of the mining environment on selected functional properties of two commercial greases thickened with lithium 12-hydroxystearate and overbased calcium sulfonate. The study conducted a comparative analysis of fresh greases and those that had been used in operation. The tests were performed in climatic conditions similar to those found in the mine. The greases were evaluated for their resistance to water washout at 38 °C, as well as their dropping point and anti-corrosion properties in the presence of brine (EMCOR method). Additionally, rheological tests were conducted to assess the behavior of the greases in the lubrication film of a real friction node. Moreover, tribological tests were carried out under varying loads on the lubricated friction node. A custom-designed test rig for measuring frictional resistance in oscillatory motion was used for these evaluations. The conclusions from the study on the impact of the mining environment on the functional properties of greases were supported by the results of their ATR-IR spectroscopic analysis. The research results showed that contaminants from the mine's atmosphere affect the functional properties and the structure of the thickeners of both greases. The greases subjected to use, compared to fresh greases, exhibited increased resistance to water washout. Most other parameters, including rheological and tribological properties, significantly deteriorated.